node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aff-1 | ajm-1 | C44B7.3.1 | C25A11.4f.1 | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | 0.453 |
aff-1 | eff-1 | C44B7.3.1 | C26D10.5a.1 | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | Epithelial Fusion Failure. | 0.402 |
ajm-1 | aff-1 | C25A11.4f.1 | C44B7.3.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | 0.453 |
ajm-1 | eff-1 | C25A11.4f.1 | C26D10.5a.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Epithelial Fusion Failure. | 0.405 |
ajm-1 | rol-6 | C25A11.4f.1 | T01B7.7.2 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | 0.699 |
ajm-1 | unc-119 | C25A11.4f.1 | M142.1c.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system. | 0.769 |
ajm-1 | unc-29 | C25A11.4f.1 | T08G11.5.2 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Acetylcholine receptor subunit beta-type unc-29; Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine and levasimole. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. | 0.670 |
eff-1 | aff-1 | C26D10.5a.1 | C44B7.3.1 | Epithelial Fusion Failure. | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | 0.402 |
eff-1 | ajm-1 | C26D10.5a.1 | C25A11.4f.1 | Epithelial Fusion Failure. | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | 0.405 |
ftt-2 | par-5 | F52D10.3a.3 | M117.2a.1 | 14-3-3-like protein 2; Required for extension of life-span by sir-2.1. Promotes nuclear export of yap-1. Negatively regulates the transcriptional activity of daf-16 by sequestering it to the cytoplasm. Belongs to the 14-3-3 family. | 14-3-3-like protein 1. | 0.658 |
myo-2 | pes-10 | T18D3.4.1 | Y46G5A.27.1 | Myosin-2; Muscle contraction. | Patterned expression site protein 10. | 0.852 |
myo-2 | rol-6 | T18D3.4.1 | T01B7.7.2 | Myosin-2; Muscle contraction. | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | 0.812 |
myo-2 | unc-119 | T18D3.4.1 | M142.1c.1 | Myosin-2; Muscle contraction. | Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system. | 0.808 |
myo-2 | unc-22 | T18D3.4.1 | ZK617.1b.1 | Myosin-2; Muscle contraction. | Twitchin; Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces. Plays a role in the organization of sarcomeres in body wall muscles ; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.773 |
par-5 | ftt-2 | M117.2a.1 | F52D10.3a.3 | 14-3-3-like protein 1. | 14-3-3-like protein 2; Required for extension of life-span by sir-2.1. Promotes nuclear export of yap-1. Negatively regulates the transcriptional activity of daf-16 by sequestering it to the cytoplasm. Belongs to the 14-3-3 family. | 0.658 |
pes-10 | myo-2 | Y46G5A.27.1 | T18D3.4.1 | Patterned expression site protein 10. | Myosin-2; Muscle contraction. | 0.852 |
pes-10 | rol-6 | Y46G5A.27.1 | T01B7.7.2 | Patterned expression site protein 10. | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | 0.533 |
pes-10 | unc-119 | Y46G5A.27.1 | M142.1c.1 | Patterned expression site protein 10. | Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system. | 0.672 |
rol-6 | ajm-1 | T01B7.7.2 | C25A11.4f.1 | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | 0.699 |
rol-6 | myo-2 | T01B7.7.2 | T18D3.4.1 | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | Myosin-2; Muscle contraction. | 0.812 |