node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ceh-36 | sra-9 | C37E2.4.1 | AH6.14.1 | Homeobox protein ceh-36; Mediates chemosensory function of ASE and AWC neurons. In ASE neurons, required to diversify the fate of the ASEL neurons from the ASER neurons. In cooperation with the transcription factor sox-2, required for the differentiation of AWC olfactory neurons. May regulate the expression of sox-2 in AWC olfactory neurons. Belongs to the paired homeobox family. | Serpentine receptor class alpha-9. | 0.663 |
ceh-36 | str-3 | C37E2.4.1 | M7.13.1 | Homeobox protein ceh-36; Mediates chemosensory function of ASE and AWC neurons. In ASE neurons, required to diversify the fate of the ASEL neurons from the ASER neurons. In cooperation with the transcription factor sox-2, required for the differentiation of AWC olfactory neurons. May regulate the expression of sox-2 in AWC olfactory neurons. Belongs to the paired homeobox family. | Seven TM Receptor. | 0.692 |
che-12 | srg-47 | B0024.8a.1 | C53A5.8.1 | Crescerin-like protein che-12; Required for normal structure and function of sensory cilia on amphid neurons, especially for the formation of distal ciliary structures, but is less important for normal assembly of middle and basal ciliary structures. Plays a role in the organization of axoneme microtubule bundles in sensory cilia. Required for normal structure and function of the ASER neuron that mediates attraction to NaCl. Required for normal chemotaxis to NaCl. Required for normal avoidance response to high osmolarity. In contrast, is not required for normal chemotaxis to isoamyl al [...] | Serpentine receptor class gamma-47. | 0.418 |
che-12 | ttbk-3 | B0024.8a.1 | F32B6.10a.1 | Crescerin-like protein che-12; Required for normal structure and function of sensory cilia on amphid neurons, especially for the formation of distal ciliary structures, but is less important for normal assembly of middle and basal ciliary structures. Plays a role in the organization of axoneme microtubule bundles in sensory cilia. Required for normal structure and function of the ASER neuron that mediates attraction to NaCl. Required for normal chemotaxis to NaCl. Required for normal avoidance response to high osmolarity. In contrast, is not required for normal chemotaxis to isoamyl al [...] | Protein kinase domain-containing protein. | 0.663 |
daf-37 | daf-7 | C30B5.5.1 | B0412.2.1 | G-protein coupled receptor daf-37; G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior. Receptor for the ascaroside pheromone ascr#2. Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2. May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion. May function upstream of the daf-11, daf-7 and daf-2 signaling pathways. | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | 0.586 |
daf-37 | srbc-64 | C30B5.5.1 | Y39G10AR.22.1 | G-protein coupled receptor daf-37; G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior. Receptor for the ascaroside pheromone ascr#2. Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2. May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion. May function upstream of the daf-11, daf-7 and daf-2 signaling pathways. | Serpentine Receptor, class BC (Class B-like). | 0.931 |
daf-37 | srbc-66 | C30B5.5.1 | T24A6.5.1 | G-protein coupled receptor daf-37; G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior. Receptor for the ascaroside pheromone ascr#2. Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2. May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion. May function upstream of the daf-11, daf-7 and daf-2 signaling pathways. | Serpentine Receptor, class BC (Class B-like). | 0.929 |
daf-37 | srg-36 | C30B5.5.1 | K04C1.6.1 | G-protein coupled receptor daf-37; G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior. Receptor for the ascaroside pheromone ascr#2. Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2. May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion. May function upstream of the daf-11, daf-7 and daf-2 signaling pathways. | Serpentine receptor class gamma; Belongs to the nematode receptor-like protein srg family. | 0.913 |
daf-37 | srg-37 | C30B5.5.1 | K04C1.1.1 | G-protein coupled receptor daf-37; G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior. Receptor for the ascaroside pheromone ascr#2. Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2. May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion. May function upstream of the daf-11, daf-7 and daf-2 signaling pathways. | Serpentine receptor class gamma; Belongs to the nematode receptor-like protein srg family. | 0.912 |
daf-7 | daf-37 | B0412.2.1 | C30B5.5.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | G-protein coupled receptor daf-37; G-protein coupled receptor (GPCR) that forms a heterodimer with daf-38 to control dauer formation and behavior. Receptor for the ascaroside pheromone ascr#2. Required for the response to dauer inducing pheromones, specifically the ascaroside ascr#2. May serve neuronal specific roles in response to ascr#2 with expression in ASI neurons controlling dauer formation in larvae, and expression in ASK neurons playing a role in longevity and hermaphrodite repulsion. May function upstream of the daf-11, daf-7 and daf-2 signaling pathways. | 0.586 |
daf-7 | ins-1 | B0412.2.1 | F13B12.5.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | IlGF domain-containing protein. | 0.709 |
daf-7 | maco-1 | B0412.2.1 | D2092.5.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | Macoilin; Plays a role in the regulation of neuronal activity. | 0.468 |
daf-7 | srbc-64 | B0412.2.1 | Y39G10AR.22.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | Serpentine Receptor, class BC (Class B-like). | 0.660 |
daf-7 | srbc-66 | B0412.2.1 | T24A6.5.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | Serpentine Receptor, class BC (Class B-like). | 0.660 |
daf-7 | srg-36 | B0412.2.1 | K04C1.6.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | Serpentine receptor class gamma; Belongs to the nematode receptor-like protein srg family. | 0.616 |
daf-7 | srg-37 | B0412.2.1 | K04C1.1.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | Serpentine receptor class gamma; Belongs to the nematode receptor-like protein srg family. | 0.588 |
daf-7 | str-3 | B0412.2.1 | M7.13.1 | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | Seven TM Receptor. | 0.693 |
ins-1 | daf-7 | F13B12.5.1 | B0412.2.1 | IlGF domain-containing protein. | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | 0.709 |
maco-1 | daf-7 | D2092.5.1 | B0412.2.1 | Macoilin; Plays a role in the regulation of neuronal activity. | Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. | 0.468 |
maco-1 | srg-47 | D2092.5.1 | C53A5.8.1 | Macoilin; Plays a role in the regulation of neuronal activity. | Serpentine receptor class gamma-47. | 0.586 |