Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| asfl-1 | cdt-1 | C03D6.5.1 | Y54E10A.15.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | CDT1 domain-containing protein. | 0.457 |
| asfl-1 | mcm-2 | C03D6.5.1 | Y17G7B.5a.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | DNA helicase; Belongs to the MCM family. | 0.908 |
| asfl-1 | mcm-6 | C03D6.5.1 | ZK632.1a.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | DNA replication licensing factor mcm-6; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentia [...] | 0.699 |
| asfl-1 | pcn-1 | C03D6.5.1 | W03D2.4.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.620 |
| cdc-6 | cdt-1 | C43E11.10.1 | Y54E10A.15.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | CDT1 domain-containing protein. | 0.999 |
| cdc-6 | mcm-10 | C43E11.10.1 | Y47D3A.28.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Mcm10 domain-containing protein. | 0.998 |
| cdc-6 | mcm-2 | C43E11.10.1 | Y17G7B.5a.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc-6 | mcm-6 | C43E11.10.1 | ZK632.1a.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor mcm-6; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentia [...] | 0.999 |
| cdc-6 | pcn-1 | C43E11.10.1 | W03D2.4.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.711 |
| cdc-6 | smc-3 | C43E11.10.1 | Y47D3A.26b.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Structural maintenance of chromosomes protein 3; Involved in chromosome cohesion during cell cycle and in DNA repair. Involved in the repair of double strand breaks during mitosis and meiosis. Required for chromosome segregation during mitosis. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chrom [...] | 0.590 |
| cdc-6 | top-1 | C43E11.10.1 | M01E5.5a.2 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] | 0.670 |
| cdc-6 | top-2 | C43E11.10.1 | K12D12.1.1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA topoisomerase 2 top-2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks (By similarity). Essential during mitosis in the adult germline and during embryogenesis for proper segregation of daughter chromosomes. Required for centromere resolution during mitosis. Required for chromosome segregation in anaphase of meiosis I during spermatogenesis. Promotes cleavage furrow stability during cytokinesis upon the presence of chromatin obstructions. Promotes DNA break formation upon zygotic genome [...] | 0.466 |
| cdt-1 | asfl-1 | Y54E10A.15.1 | C03D6.5.1 | CDT1 domain-containing protein. | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.457 |
| cdt-1 | cdc-6 | Y54E10A.15.1 | C43E11.10.1 | CDT1 domain-containing protein. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
| cdt-1 | mcm-10 | Y54E10A.15.1 | Y47D3A.28.1 | CDT1 domain-containing protein. | Mcm10 domain-containing protein. | 0.998 |
| cdt-1 | mcm-2 | Y54E10A.15.1 | Y17G7B.5a.1 | CDT1 domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdt-1 | mcm-6 | Y54E10A.15.1 | ZK632.1a.1 | CDT1 domain-containing protein. | DNA replication licensing factor mcm-6; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentia [...] | 0.999 |
| cdt-1 | pcn-1 | Y54E10A.15.1 | W03D2.4.1 | CDT1 domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.968 |
| cdt-1 | smo-1 | Y54E10A.15.1 | K12C11.2.1 | CDT1 domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.531 |
| cdt-1 | top-1 | Y54E10A.15.1 | M01E5.5a.2 | CDT1 domain-containing protein. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] | 0.672 |
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