STRINGSTRING
sodh-1 sodh-1 let-70 let-70 lips-6 lips-6 oac-56 oac-56 Y65B4BR.1 Y65B4BR.1 nhr-13 nhr-13 paqr-2 paqr-2 fat-5 fat-5 W02B12.1 W02B12.1 fat-6 fat-6 act-5 act-5 nhr-69 nhr-69 nhr-66 nhr-66 mdt-15 mdt-15 mboa-1 mboa-1 icl-1 icl-1 gei-8 gei-8 dhs-18 dhs-18 din-1 din-1 cpt-5 cpt-5 fat-7 fat-7 ddo-2 ddo-2 tba-1 tba-1 acs-2 acs-2 nhr-8 nhr-8 nhr-80 nhr-80 mboa-2 mboa-2 nhr-49 nhr-49
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sodh-1Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. (349 aa)
let-70Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
lips-6LIPaSe related. (344 aa)
oac-56Acyl_transf_3 domain-containing protein. (644 aa)
Y65B4BR.1Lipase_GDSL domain-containing protein. (377 aa)
nhr-13Nuclear hormone receptor family member nhr-13; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. (425 aa)
paqr-2Progestin and AdipoQ Receptor family. (581 aa)
fat-5Delta(9)-fatty-acid desaturase fat-5; Delta(9)-fatty-acid desaturase that acts preferentially on palmitoyl-CoA. Also acts on pentadecanoyl-coA and myristoyl-CoA. (333 aa)
W02B12.1Lipase_GDSL domain-containing protein. (382 aa)
fat-6Delta(9)-fatty-acid desaturase fat-6; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. Belongs to the fatty acid desaturase type 1 family. (339 aa)
act-5ACTin. (375 aa)
nhr-69Nuclear hormone receptor family member nhr-69; Orphan nuclear receptor. (373 aa)
nhr-66Nuclear Hormone Receptor family. (733 aa)
mdt-15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Require [...] (780 aa)
mboa-1O-acyltransferase. (467 aa)
icl-1Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family. (968 aa)
gei-8Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. (1778 aa)
dhs-18DeHydrogenases, Short chain. (293 aa)
din-1Daf-12-interacting protein 1; [Isoform d]: Probable transcriptional corepressor which modulates activity of the nuclear hormone receptor daf-12 to regulate the dauer diapause. (2407 aa)
cpt-5Carn_acyltransf domain-containing protein. (735 aa)
fat-7Delta(9)-fatty-acid desaturase fat-7; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA, heptadecanyol-CoA, and palmitoyl-CoA. (338 aa)
ddo-2D-aspartate oxidase 2; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA. May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells. (334 aa)
tba-1Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
acs-2Fatty Acid CoA Synthetase family. (618 aa)
nhr-8Nuclear hormone receptor family member nhr-8; Orphan nuclear receptor. (560 aa)
nhr-80Nuclear Hormone Receptor family. (504 aa)
mboa-2O-acyltransferase. (498 aa)
nhr-49Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. (501 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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