Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| act-5 | acy-1 | T25C8.2.2 | F17C8.1.1 | ACTin. | Adenylyl CYclase. | 0.446 |
| act-5 | acy-2 | T25C8.2.2 | C10F3.3.1 | ACTin. | Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.438 |
| act-5 | acy-3 | T25C8.2.2 | C44F1.5.2 | ACTin. | Adenylyl CYclase. | 0.470 |
| act-5 | cul-1 | T25C8.2.2 | D2045.6.1 | ACTin. | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | 0.490 |
| act-5 | hsp-70 | T25C8.2.2 | C12C8.1.1 | ACTin. | Heat Shock Protein; Belongs to the heat shock protein 70 family. | 0.946 |
| act-5 | hsp-90 | T25C8.2.2 | C47E8.5.3 | ACTin. | Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] | 0.914 |
| act-5 | plk-1 | T25C8.2.2 | C14B9.4b.1 | ACTin. | Serine/threonine-protein kinase plk-1; Required for oocyte nuclear envelope breakdown before entry of oocyte into spermatheca. In meiotic cells, required for spindle dynamics and probably for spindle attachment to the chromosomes. Zygotic role in the development of the germline and nerve cord. In mitotic cells, plays a role in spindle organization and centrosome maturation. Involved in asymmetric nuclear localization of cdc- 25.1 during embryogenesis which affects cell division timing. Together with plk- 2, regulates cytoplasm polarity in early embryos. May play a minor role in chromos [...] | 0.734 |
| act-5 | plk-2 | T25C8.2.2 | Y71F9B.7.1 | ACTin. | Serine/threonine-protein kinase plk-2; Serine/threonine-protein kinase which plays a role, during oogenesis, in chromosome pairing and synapsis, by facilitating the recruitment and attachment of meiotic chromosomes to the nuclear envelope during prophase. Regulates the formation of sun-1 patches along the nuclear envelope. Promotes meiotic nuclei apoptosis in response to chromosomal asynapsis. Plays a redundant role with plk-1 in the establishment of cell polarity downstream of mex-5 and mex-6 during the first embryonic cell divisions. Plays a role in nicotinic acetylcholine receptor- [...] | 0.435 |
| act-5 | plk-3 | T25C8.2.2 | F55G1.8.2 | ACTin. | Serine/threonine-protein kinase plk-3; May be required for cell division and may have a role during G1 or S phase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. | 0.408 |
| acy-1 | act-5 | F17C8.1.1 | T25C8.2.2 | Adenylyl CYclase. | ACTin. | 0.446 |
| acy-1 | acy-2 | F17C8.1.1 | C10F3.3.1 | Adenylyl CYclase. | Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.484 |
| acy-1 | acy-3 | F17C8.1.1 | C44F1.5.2 | Adenylyl CYclase. | Adenylyl CYclase. | 0.463 |
| acy-2 | act-5 | C10F3.3.1 | T25C8.2.2 | Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | ACTin. | 0.438 |
| acy-2 | acy-1 | C10F3.3.1 | F17C8.1.1 | Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Adenylyl CYclase. | 0.484 |
| acy-3 | act-5 | C44F1.5.2 | T25C8.2.2 | Adenylyl CYclase. | ACTin. | 0.470 |
| acy-3 | acy-1 | C44F1.5.2 | F17C8.1.1 | Adenylyl CYclase. | Adenylyl CYclase. | 0.463 |
| cul-1 | act-5 | D2045.6.1 | T25C8.2.2 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | ACTin. | 0.490 |
| cul-1 | hsp-90 | D2045.6.1 | C47E8.5.3 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] | 0.494 |
| cul-1 | plk-1 | D2045.6.1 | C14B9.4b.1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | Serine/threonine-protein kinase plk-1; Required for oocyte nuclear envelope breakdown before entry of oocyte into spermatheca. In meiotic cells, required for spindle dynamics and probably for spindle attachment to the chromosomes. Zygotic role in the development of the germline and nerve cord. In mitotic cells, plays a role in spindle organization and centrosome maturation. Involved in asymmetric nuclear localization of cdc- 25.1 during embryogenesis which affects cell division timing. Together with plk- 2, regulates cytoplasm polarity in early embryos. May play a minor role in chromos [...] | 0.652 |
| cul-1 | plk-2 | D2045.6.1 | Y71F9B.7.1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | Serine/threonine-protein kinase plk-2; Serine/threonine-protein kinase which plays a role, during oogenesis, in chromosome pairing and synapsis, by facilitating the recruitment and attachment of meiotic chromosomes to the nuclear envelope during prophase. Regulates the formation of sun-1 patches along the nuclear envelope. Promotes meiotic nuclei apoptosis in response to chromosomal asynapsis. Plays a redundant role with plk-1 in the establishment of cell polarity downstream of mex-5 and mex-6 during the first embryonic cell divisions. Plays a role in nicotinic acetylcholine receptor- [...] | 0.709 |
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