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cdk-5 | Cyclin-dependent-like kinase 5; Proline-directed serine/threonine-protein kinase which, in several motor neurons, promotes the polarized trafficking of synaptic vesicles and dense-core vesicles (DCV). In the ventral nerve cord, phosphorylates lin-10 and thereby prevents lin-10-mediated anterograde trafficking of the glutamate receptor glr-1. Involved in the inhibition of glr-1 trafficking in hypoxic conditions. In DA motor neurons but not in DB motor neurons, regulates axonal transport of synaptic vesicle precursors by inhibiting dynein-mediated retrograde transport. Regulates the traf [...] (292 aa) | ||||
rab-3 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. (233 aa) | ||||
rab-1 | RAB family. (205 aa) | ||||
rab-8 | RAB family. (211 aa) | ||||
rab-5 | RAB family. (208 aa) | ||||
sph-1 | MARVEL domain-containing protein. (227 aa) | ||||
rab-14 | RAB family. (210 aa) | ||||
rab-21 | RAB family. (207 aa) | ||||
eea-1 | FYVE-type domain-containing protein. (1205 aa) | ||||
rab-10 | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] (201 aa) | ||||
rab-7 | RAB family. (209 aa) | ||||
arf-6 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. (175 aa) | ||||
rabs-5 | FYVE-type domain-containing protein. (565 aa) | ||||
rab-35 | RAB family. (209 aa) | ||||
aex-6 | Rab27. (215 aa) | ||||
ZK970.8 | Uncharacterized protein. (143 aa) |