STRINGSTRING
lin-39 lin-39 egl-6 egl-6 egl-47 egl-47 flp-17 flp-17 egl-10 egl-10 irk-1 irk-1 flp-10 flp-10 mec-7 mec-7 dgk-1 dgk-1 goa-1 goa-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lin-39Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] (253 aa)
egl-6G_PROTEIN_RECEP_F1_2 domain-containing protein. (395 aa)
egl-47Egg laying defective EGL-47A; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. (522 aa)
flp-17FMRF-Like Peptide. (130 aa)
egl-10Regulator of G-protein signaling egl-10; Involved in egg-laying and locomotion. May regulate G protein goa-1 signaling. (639 aa)
irk-1Inward rectifier potassium channel irk-1; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior. (544 aa)
flp-10FMRFamide-like peptide 10. (67 aa)
mec-7Tubulin beta-1 chain; Tubulin is the major constituent of microtubules (Probable). It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (Probable). Plays a role in mechanosensory transduction (touch sensitivity). (441 aa)
dgk-1Diacylglycerol kinase. (952 aa)
goa-1Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. In the 1-cell embryo, probably together with gpa-16, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisions, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create [...] (354 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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