STRINGSTRING
stam-1 stam-1 rab-5 rab-5 gpd-4 gpd-4 dna-2 dna-2 gpd-3 gpd-3 gpd-2 gpd-2 gpd-1 gpd-1 chc-1 chc-1 hgrs-1 hgrs-1 tsg-101 tsg-101
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
stam-1Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa)
rab-5RAB family. (208 aa)
gpd-4Glyceraldehyde-3-phosphate dehydrogenase 4. (341 aa)
dna-2Yeast DNA helicase/endonuclease family. (1069 aa)
gpd-3Glyceraldehyde-3-phosphate dehydrogenase 3. (341 aa)
gpd-2Glyceraldehyde-3-phosphate dehydrogenase 2. (341 aa)
gpd-1Glyceraldehyde-3-phosphate dehydrogenase 1. (341 aa)
chc-1Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. (1681 aa)
hgrs-1Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. (729 aa)
tsg-101Tumor Susceptibility Gene homolog. (425 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (32%) [HD]