STRINGSTRING
daf-7 daf-7 daf-4 daf-4 sma-6 sma-6 acox-1.5 acox-1.5 acdh-1 acdh-1 ech-8 ech-8 ech-9 ech-9 daf-14 daf-14 daf-3 daf-3 daf-1 daf-1 dpy-7 dpy-7 acox-1.6 acox-1.6 daf-8 daf-8 rol-6 rol-6 sma-9 sma-9 ech-6 ech-6 myo-2 myo-2 rpl-32 rpl-32 dbl-1 dbl-1 vha-6 vha-6 daf-5 daf-5 cpt-3 cpt-3 fzo-1 fzo-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
daf-7Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. (350 aa)
daf-4Cell surface receptor daf-4; Involved in TGF-beta pathway. May be a receptor for daf-7. Controls the dauer/nondauer developmental decision in a range of environmental conditions. Regulates body size and male tail patterning. Involved in regulating entry into quiescence triggered by satiety. Involved in sensitivity to CO2 levels. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (744 aa)
sma-6Serine/threonine-protein kinase sma-6; Involved in TGF-beta pathway. May be a receptor for daf-7; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (636 aa)
acox-1.5Probable peroxisomal acyl-coenzyme A oxidase 1.5; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (659 aa)
acdh-1Acyl CoA DeHydrogenase. (427 aa)
ech-8Enoyl-CoA Hydratase. (437 aa)
ech-9Enoyl-CoA Hydratase. (434 aa)
daf-14MH2 domain-containing protein. (331 aa)
daf-3Dwarfin sma. (895 aa)
daf-1Cell surface receptor daf-1; Controls the dauer/nondauer developmental decision in a range of environmental conditions. Involved in regulating entry into quiescence triggered by satiety. Involved in sensitivity to CO2 levels. (669 aa)
dpy-7Cuticle collagen dpy-7; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-7 affects the body shape. (318 aa)
acox-1.6Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (667 aa)
daf-8Dwarfin sma. (546 aa)
rol-6Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. (348 aa)
sma-9SMAll. (2232 aa)
ech-6Probable enoyl-CoA hydratase, mitochondrial. (288 aa)
myo-2Myosin-2; Muscle contraction. (1947 aa)
rpl-32Ribosomal Protein, Large subunit. (134 aa)
dbl-1TGF_BETA_2 domain-containing protein. (365 aa)
vha-6V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (865 aa)
daf-5C-SKI_SMAD_bind domain-containing protein. (627 aa)
cpt-3Carn_acyltransf domain-containing protein. (722 aa)
fzo-1Transmembrane GTPase fzo-1; Probable transmembrane GTPase (By similarity). Mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily. (774 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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