node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdk-1 | dna-2 | T05G5.3.2 | F43G6.1.1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | Yeast DNA helicase/endonuclease family. | 0.583 |
cdk-1 | exo-1 | T05G5.3.2 | F45G2.3.1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | EXOnuclease. | 0.758 |
cdk-1 | hsr-9 | T05G5.3.2 | T05F1.6.1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | 0.695 |
cdk-1 | lig-1 | T05G5.3.2 | C29A12.3a.1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.514 |
dna-2 | cdk-1 | F43G6.1.1 | T05G5.3.2 | Yeast DNA helicase/endonuclease family. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | 0.583 |
dna-2 | exo-1 | F43G6.1.1 | F45G2.3.1 | Yeast DNA helicase/endonuclease family. | EXOnuclease. | 0.998 |
dna-2 | hsr-9 | F43G6.1.1 | T05F1.6.1 | Yeast DNA helicase/endonuclease family. | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | 0.962 |
dna-2 | lig-1 | F43G6.1.1 | C29A12.3a.1 | Yeast DNA helicase/endonuclease family. | DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.941 |
dna-2 | rad-50 | F43G6.1.1 | T04H1.4b.2 | Yeast DNA helicase/endonuclease family. | DNA repair protein rad-50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity. | 0.479 |
dna-2 | top-1 | F43G6.1.1 | M01E5.5a.2 | Yeast DNA helicase/endonuclease family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] | 0.803 |
exo-1 | cdk-1 | F45G2.3.1 | T05G5.3.2 | EXOnuclease. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | 0.758 |
exo-1 | dna-2 | F45G2.3.1 | F43G6.1.1 | EXOnuclease. | Yeast DNA helicase/endonuclease family. | 0.998 |
exo-1 | hsr-9 | F45G2.3.1 | T05F1.6.1 | EXOnuclease. | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | 0.973 |
exo-1 | lig-1 | F45G2.3.1 | C29A12.3a.1 | EXOnuclease. | DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.968 |
exo-1 | rad-50 | F45G2.3.1 | T04H1.4b.2 | EXOnuclease. | DNA repair protein rad-50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity. | 0.808 |
exo-1 | top-1 | F45G2.3.1 | M01E5.5a.2 | EXOnuclease. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] | 0.836 |
hsr-9 | cdk-1 | T05F1.6.1 | T05G5.3.2 | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | 0.695 |
hsr-9 | dna-2 | T05F1.6.1 | F43G6.1.1 | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | Yeast DNA helicase/endonuclease family. | 0.962 |
hsr-9 | exo-1 | T05F1.6.1 | F45G2.3.1 | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | EXOnuclease. | 0.973 |
hsr-9 | lig-1 | T05F1.6.1 | C29A12.3a.1 | Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. | DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.720 |