Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Y37B11A.2 | brc-1 | Y37B11A.2a.1 | C36A4.8a.1 | DNA polymerase. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of polyubiquitin chains and plays a central role in DNA repair. Plays a role in triggering cellular responses at damage sites in response to DNA damage that may be induced by UV and ionizing radiation for example. Functions in double-strand break repair, and is required for homologous recombination between sister chromatids in meiotic and mitotic cells. In particular, protects against chromosome non-disjunction and nuclear fragmentation during meiotic double-strand [...] | 0.500 |
| Y37B11A.2 | gen-1 | Y37B11A.2a.1 | T12A2.8.2 | DNA polymerase. | GEN1 Holliday junction resolvase homolog. | 0.724 |
| Y37B11A.2 | lig-4 | Y37B11A.2a.1 | C07H6.1.1 | DNA polymerase. | LIGase. | 0.768 |
| Y37B11A.2 | pola-1 | Y37B11A.2a.1 | Y47D3A.29b.1 | DNA polymerase. | DNA polymerase. | 0.771 |
| Y37B11A.2 | polh-1 | Y37B11A.2a.1 | F53A3.2.1 | DNA polymerase. | UmuC domain-containing protein. | 0.990 |
| Y37B11A.2 | polq-1 | Y37B11A.2a.1 | W03A3.2.1 | DNA polymerase. | DNA polymerase theta; DNA polymerase that promotes microhomology-mediated end- joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions. Required to prevent extensive loss of sequences near G-quadruplex (G4) DNA sites, which are prone to cause genome alterations, by generating deletions. | 0.907 |
| Y37B11A.2 | xpf-1 | Y37B11A.2a.1 | C47D12.8.1 | DNA polymerase. | ERCC4 domain-containing protein. | 0.846 |
| ZK430.5 | bub-1 | ZK430.5.1 | R06C7.8.1 | Peptidase C50 domain-containing protein. | Mitotic checkpoint serine/threonine-protein kinase bub-1; Serine/threonine-protein kinase essential for spindle- assembly checkpoint signaling. Plays a key role in the recruitment of the checkpoint proteins bub-3, mdf-1 and mdf-2 to unattached kinetochores. mdf-1 recruitment is independent of bub-1 kinase activity. Has a role in the correct kinetochore localization of the spindly-like protein spdl-1. In addition, during meiotic anaphase I, controls the recruitment of hcp- 1/2 and klp-19 to the ring-shaped domain formed between chromosomes. Involved in chromosome alignment, chromosome h [...] | 0.931 |
| ZK430.5 | bub-3 | ZK430.5.1 | Y54G9A.6.1 | Peptidase C50 domain-containing protein. | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. | 0.941 |
| ZK430.5 | cdk-1 | ZK430.5.1 | T05G5.3.2 | Peptidase C50 domain-containing protein. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | 0.968 |
| ZK430.5 | fzy-1 | ZK430.5.1 | ZK177.6.1 | Peptidase C50 domain-containing protein. | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | 0.816 |
| ZK430.5 | his-39 | ZK430.5.1 | F45F2.2.1 | Peptidase C50 domain-containing protein. | Histone domain-containing protein; Belongs to the histone H2B family. | 0.419 |
| ZK430.5 | his-41 | ZK430.5.1 | C50F4.5.1 | Peptidase C50 domain-containing protein. | Probable histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.463 |
| ZK430.5 | his-44 | ZK430.5.1 | F08G2.1.1 | Peptidase C50 domain-containing protein. | Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.419 |
| ZK430.5 | his-48 | ZK430.5.1 | B0035.8.1 | Peptidase C50 domain-containing protein. | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.424 |
| ZK430.5 | his-54 | ZK430.5.1 | F07B7.11.1 | Peptidase C50 domain-containing protein. | Histone H2B 2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.419 |
| brc-1 | Y37B11A.2 | C36A4.8a.1 | Y37B11A.2a.1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of polyubiquitin chains and plays a central role in DNA repair. Plays a role in triggering cellular responses at damage sites in response to DNA damage that may be induced by UV and ionizing radiation for example. Functions in double-strand break repair, and is required for homologous recombination between sister chromatids in meiotic and mitotic cells. In particular, protects against chromosome non-disjunction and nuclear fragmentation during meiotic double-strand [...] | DNA polymerase. | 0.500 |
| brc-1 | cdk-1 | C36A4.8a.1 | T05G5.3.2 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of polyubiquitin chains and plays a central role in DNA repair. Plays a role in triggering cellular responses at damage sites in response to DNA damage that may be induced by UV and ionizing radiation for example. Functions in double-strand break repair, and is required for homologous recombination between sister chromatids in meiotic and mitotic cells. In particular, protects against chromosome non-disjunction and nuclear fragmentation during meiotic double-strand [...] | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). | 0.401 |
| brc-1 | fzy-1 | C36A4.8a.1 | ZK177.6.1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of polyubiquitin chains and plays a central role in DNA repair. Plays a role in triggering cellular responses at damage sites in response to DNA damage that may be induced by UV and ionizing radiation for example. Functions in double-strand break repair, and is required for homologous recombination between sister chromatids in meiotic and mitotic cells. In particular, protects against chromosome non-disjunction and nuclear fragmentation during meiotic double-strand [...] | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | 0.633 |
| brc-1 | gen-1 | C36A4.8a.1 | T12A2.8.2 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of polyubiquitin chains and plays a central role in DNA repair. Plays a role in triggering cellular responses at damage sites in response to DNA damage that may be induced by UV and ionizing radiation for example. Functions in double-strand break repair, and is required for homologous recombination between sister chromatids in meiotic and mitotic cells. In particular, protects against chromosome non-disjunction and nuclear fragmentation during meiotic double-strand [...] | GEN1 Holliday junction resolvase homolog. | 0.783 |
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