Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| daf-12 | din-1 | F11A1.3a.1 | F07A11.6b.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Daf-12-interacting protein 1; [Isoform d]: Probable transcriptional corepressor which modulates activity of the nuclear hormone receptor daf-12 to regulate the dauer diapause. | 0.964 |
| daf-12 | fax-1 | F11A1.3a.1 | F56E3.4a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Nuclear receptor domain-containing protein. | 0.453 |
| daf-12 | nhr-25 | F11A1.3a.1 | F11C1.6a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | 0.654 |
| daf-12 | nhr-48 | F11A1.3a.1 | ZK662.3b.2 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Nuclear hormone receptor family member nhr-48; Orphan nuclear receptor. | 0.409 |
| daf-12 | nhr-49 | F11A1.3a.1 | K10C3.6c.2 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. | 0.406 |
| daf-12 | nhr-8 | F11A1.3a.1 | F33D4.1a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Nuclear hormone receptor family member nhr-8; Orphan nuclear receptor. | 0.491 |
| din-1 | daf-12 | F07A11.6b.1 | F11A1.3a.1 | Daf-12-interacting protein 1; [Isoform d]: Probable transcriptional corepressor which modulates activity of the nuclear hormone receptor daf-12 to regulate the dauer diapause. | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | 0.964 |
| din-1 | nhr-48 | F07A11.6b.1 | ZK662.3b.2 | Daf-12-interacting protein 1; [Isoform d]: Probable transcriptional corepressor which modulates activity of the nuclear hormone receptor daf-12 to regulate the dauer diapause. | Nuclear hormone receptor family member nhr-48; Orphan nuclear receptor. | 0.702 |
| din-1 | nhr-8 | F07A11.6b.1 | F33D4.1a.1 | Daf-12-interacting protein 1; [Isoform d]: Probable transcriptional corepressor which modulates activity of the nuclear hormone receptor daf-12 to regulate the dauer diapause. | Nuclear hormone receptor family member nhr-8; Orphan nuclear receptor. | 0.531 |
| fax-1 | daf-12 | F56E3.4a.1 | F11A1.3a.1 | Nuclear receptor domain-containing protein. | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | 0.453 |
| lin-39 | nhr-25 | C07H6.7.2 | F11C1.6a.1 | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | 0.660 |
| lin-39 | nhr-67 | C07H6.7.2 | C08F8.8.1 | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | Nuclear hormone receptor family member nhr-67; Orphan nuclear receptor. In males, plays an essential role in the migration of the linker cell which guides gonad elongation during the L3 and L4 stages of larval development by negatively regulating the expression of netrin receptor unc-5 at the mid-L3 stage. | 0.413 |
| lin-39 | unc-55 | C07H6.7.2 | F55D12.4a.1 | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | Nuclear hormone receptor unc-55; Acts as a transcriptional regulator. Required for ventral D (VD) motor neurons to adopt their normal synaptic pattern. Suppresses expression of flp-13 in VD motor neurons to ensure formation of the correct synaptic pattern. Maintains low cAMP levels in VD motor neurons by enhancing expression of pde-4 which hydrolyzes cAMP and repressing expression of acy-1 which catalyzes cAMP formation. This prevents respecification of synapses by VD neurons. During copulation, required in males for correct movement of the spicules, a pair of prong-like structures whi [...] | 0.402 |
| nhr-114 | nhr-31 | Y45G5AM.1a.2 | C26B2.3a.1 | NR LBD domain-containing protein; Belongs to the nuclear hormone receptor family. | Nuclear hormone receptor family member nhr-31; Orphan nuclear receptor. | 0.443 |
| nhr-114 | nhr-49 | Y45G5AM.1a.2 | K10C3.6c.2 | NR LBD domain-containing protein; Belongs to the nuclear hormone receptor family. | Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. | 0.443 |
| nhr-13 | nhr-49 | Y5H2B.2b.2 | K10C3.6c.2 | Nuclear hormone receptor family member nhr-13; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. | 0.749 |
| nhr-23 | nhr-25 | C01H6.5a.1 | F11C1.6a.1 | Nuclear hormone receptor family member nhr-23; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. NR1 subfamily. | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | 0.534 |
| nhr-25 | daf-12 | F11C1.6a.1 | F11A1.3a.1 | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | 0.654 |
| nhr-25 | lin-39 | F11C1.6a.1 | C07H6.7.2 | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | 0.660 |
| nhr-25 | nhr-23 | F11C1.6a.1 | C01H6.5a.1 | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | Nuclear hormone receptor family member nhr-23; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. NR1 subfamily. | 0.534 |
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