STRINGSTRING
klf-2 klf-2 hsp-70 hsp-70 cya-2 cya-2 plk-2 plk-2 cya-1 cya-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
klf-2Kruppel-Like Factor (Zinc finger protein). (299 aa)
hsp-70Heat Shock Protein; Belongs to the heat shock protein 70 family. (643 aa)
cya-2CYCLIN domain-containing protein; Belongs to the cyclin family. (123 aa)
plk-2Serine/threonine-protein kinase plk-2; Serine/threonine-protein kinase which plays a role, during oogenesis, in chromosome pairing and synapsis, by facilitating the recruitment and attachment of meiotic chromosomes to the nuclear envelope during prophase. Regulates the formation of sun-1 patches along the nuclear envelope. Promotes meiotic nuclei apoptosis in response to chromosomal asynapsis. Plays a redundant role with plk-1 in the establishment of cell polarity downstream of mex-5 and mex-6 during the first embryonic cell divisions. Plays a role in nicotinic acetylcholine receptor- [...] (632 aa)
cya-1G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. (485 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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