STRINGSTRING
act-5 act-5 tbp-1 tbp-1 cdt-2 cdt-2 cyb-2.2 cyb-2.2 hus-1 hus-1 cdc-6 cdc-6 cdt-1 cdt-1 cyb-2.1 cyb-2.1 pcn-1 pcn-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
act-5ACTin. (375 aa)
tbp-1TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (340 aa)
cdt-2WD_REPEATS_REGION domain-containing protein. (682 aa)
cyb-2.2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (339 aa)
hus-1Checkpoint protein. (277 aa)
cdc-6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (518 aa)
cdt-1CDT1 domain-containing protein. (684 aa)
cyb-2.1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (317 aa)
pcn-1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (263 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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