17 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mtl-1	Metallothionein-1; This protein binds cations of several transition elements. (75 aa)
	fil-1	Fasting Induced Lipase. (329 aa)
	cht-2	CHiTinase; Belongs to the glycosyl hydrolase 18 family. (626 aa)
	hsp-16.11	Heat shock protein Hsp-16.1/Hsp-16.11. (145 aa)
	cht-4	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (360 aa)
	hsp-16.1	Heat shock protein Hsp-16.1/Hsp-16.11. (145 aa)
	ZK593.3	Uncharacterized protein. (147 aa)
	Y65B4BR.1	Lipase_GDSL domain-containing protein. (377 aa)
	clec-174	C-type lectin domain-containing protein. (456 aa)
	cht-1	Probable endochitinase. (617 aa)
	hsp-70	Heat Shock Protein; Belongs to the heat shock protein 70 family. (643 aa)
	hsp-3	Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. (661 aa)
	unc-104	Kinesin-like protein unc-104; Motor protein involved in microtubule-associated anterograde transport. Regulates the transport of synaptic vesicle precursors in the axon of DA motor neurons. Regulates the polarized sorting of axonal proteins. Essential for the transport of synaptic components during the synaptic remodeling of the DD motor neuron, probably downstream of cdk-5 and/or pct-1/cyy-1 complex. Required for the anterograde transport of neuropeptide-containing dense core vesicles along axons. Involved in necrotic cell death. Belongs to the TRAFAC class myosin-kinesin ATPase super [...] (1628 aa)
	acdh-1	Acyl CoA DeHydrogenase. (427 aa)
	cut-3	ZP domain-containing protein. (389 aa)
	hsp-4	Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. (657 aa)
	F49C12.7	CHK domain-containing protein. (448 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F49C12.7	Y65B4BR.1	F49C12.7b.1	Y65B4BR.1.1	CHK domain-containing protein.	Lipase_GDSL domain-containing protein.	0.748
F49C12.7	ZK593.3	F49C12.7b.1	ZK593.3.1	CHK domain-containing protein.	Uncharacterized protein.	0.913
F49C12.7	clec-174	F49C12.7b.1	Y46C8AL.2.1	CHK domain-containing protein.	C-type lectin domain-containing protein.	0.792
F49C12.7	cut-3	F49C12.7b.1	F22B5.3.1	CHK domain-containing protein.	ZP domain-containing protein.	0.758
F49C12.7	fil-1	F49C12.7b.1	T01C3.4.1	CHK domain-containing protein.	Fasting Induced Lipase.	0.707
F49C12.7	hsp-3	F49C12.7b.1	C15H9.6a.5	CHK domain-containing protein.	Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.	0.536
Y65B4BR.1	F49C12.7	Y65B4BR.1.1	F49C12.7b.1	Lipase_GDSL domain-containing protein.	CHK domain-containing protein.	0.748
Y65B4BR.1	ZK593.3	Y65B4BR.1.1	ZK593.3.1	Lipase_GDSL domain-containing protein.	Uncharacterized protein.	0.741
Y65B4BR.1	clec-174	Y65B4BR.1.1	Y46C8AL.2.1	Lipase_GDSL domain-containing protein.	C-type lectin domain-containing protein.	0.416
Y65B4BR.1	fil-1	Y65B4BR.1.1	T01C3.4.1	Lipase_GDSL domain-containing protein.	Fasting Induced Lipase.	0.438
ZK593.3	F49C12.7	ZK593.3.1	F49C12.7b.1	Uncharacterized protein.	CHK domain-containing protein.	0.913
ZK593.3	Y65B4BR.1	ZK593.3.1	Y65B4BR.1.1	Uncharacterized protein.	Lipase_GDSL domain-containing protein.	0.741
ZK593.3	acdh-1	ZK593.3.1	C55B7.4a.1	Uncharacterized protein.	Acyl CoA DeHydrogenase.	0.405
ZK593.3	clec-174	ZK593.3.1	Y46C8AL.2.1	Uncharacterized protein.	C-type lectin domain-containing protein.	0.760
ZK593.3	cut-3	ZK593.3.1	F22B5.3.1	Uncharacterized protein.	ZP domain-containing protein.	0.758
ZK593.3	fil-1	ZK593.3.1	T01C3.4.1	Uncharacterized protein.	Fasting Induced Lipase.	0.698
ZK593.3	hsp-3	ZK593.3.1	C15H9.6a.5	Uncharacterized protein.	Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.	0.536
acdh-1	ZK593.3	C55B7.4a.1	ZK593.3.1	Acyl CoA DeHydrogenase.	Uncharacterized protein.	0.405
cht-1	cht-4	C04F6.3.1	Y22D7AL.14.1	Probable endochitinase.	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	0.917
cht-4	cht-1	Y22D7AL.14.1	C04F6.3.1	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	Probable endochitinase.	0.917