Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| act-5 | ani-1 | T25C8.2.2 | Y49E10.19.1 | ACTin. | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | 0.743 |
| act-5 | arx-1 | T25C8.2.2 | Y71F9AL.16.1 | ACTin. | Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). | 0.673 |
| act-5 | arx-2 | T25C8.2.2 | K07C5.1.1 | ACTin. | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). | 0.813 |
| act-5 | atn-1 | T25C8.2.2 | W04D2.1a.1 | ACTin. | AcTiniN. | 0.998 |
| act-5 | cdc-42 | T25C8.2.2 | R07G3.1.1 | ACTin. | Cell division control protein 42 homolog; Plays an essential role in spindle orientation and organizing cellular and embryonic polarity by controlling the localization and activity of PAR (partitioning-defective) proteins. Required for maintaining the asymmetric cortical localization of the anterior complex proteins par-3 and par-6, the posterior cortical protein par-2, and pkc-3. Involved in hypodermal cell fusion, together with pak-1 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. During gonad morphogenesis, plays a role in dista [...] | 0.976 |
| act-5 | cpn-3 | T25C8.2.2 | F28H1.2.1 | ACTin. | Calponin-homology (CH) domain-containing protein. | 0.986 |
| act-5 | cpn-4 | T25C8.2.2 | F49D11.8.1 | ACTin. | Calponin-homology (CH) domain-containing protein. | 0.987 |
| act-5 | cyk-1 | T25C8.2.2 | F11H8.4b.1 | ACTin. | CYtoKinesis defect. | 0.900 |
| act-5 | erm-1 | T25C8.2.2 | C01G8.5b.1 | ACTin. | FERM domain-containing protein. | 0.816 |
| act-5 | nex-1 | T25C8.2.2 | ZC155.1.2 | ACTin. | Annexin. | 0.846 |
| act-5 | nmy-2 | T25C8.2.2 | F20G4.3.1 | ACTin. | Non-muscle MYosin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.961 |
| act-5 | pfn-1 | T25C8.2.2 | Y18D10A.20.1 | ACTin. | Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Also binds to poly(L-proline) and phosphatidylinositol 4,5-bisphosphate micelles. | 0.999 |
| act-5 | pfn-2 | T25C8.2.2 | F35C8.6.1 | ACTin. | Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity). | 0.999 |
| act-5 | pfn-3 | T25C8.2.2 | K03E6.6.1 | ACTin. | Profilin-3; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Also binds to poly(L-proline) and phosphatidylinositol 4,5-bisphosphate micelles. | 0.999 |
| act-5 | pie-1 | T25C8.2.2 | Y49E10.14a.1 | ACTin. | Pharynx and intestine in excess protein 1; Maternally provided PIE-1 is required for germline cell fate determination. Functions as a repressor of RNA polymerase II-dependent gene expression in the developing germline. Required for expression of nos-2 in P4 germline blastomere cells. Inhibits the histone deacetylase activity of hda-1. Represses transcriptional activation of cdk-9 and cit-1.1, which are members of the P-TEFb complex. | 0.482 |
| act-5 | pkc-3 | T25C8.2.2 | F09E5.1.1 | ACTin. | Protein kinase C-like 3; Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury. | 0.871 |
| act-5 | plst-1 | T25C8.2.2 | Y104H12BR.1b.1 | ACTin. | PLaSTin (Actin bundling protein) homolog. | 0.759 |
| act-5 | rga-3 | T25C8.2.2 | K09H11.3.1 | ACTin. | Rho-GAP domain-containing protein. | 0.515 |
| act-5 | rho-1 | T25C8.2.2 | Y51H4A.3a.1 | ACTin. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.989 |
| act-5 | spc-1 | T25C8.2.2 | K10B3.10b.1 | ACTin. | SPeCtrin. | 0.587 |
page 1 of 18