Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F15E6.3 | car-1 | F15E6.3.1 | Y18D10A.17.1 | RRM-type RNA binding protein. | Cytokinesis, Apoptosis, RNA-associated. | 0.663 |
| F15E6.3 | cgh-1 | F15E6.3.1 | C07H6.5.1 | RRM-type RNA binding protein. | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.775 |
| F15E6.3 | cpb-3 | F15E6.3.1 | B0414.5.1 | RRM-type RNA binding protein. | Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis. | 0.536 |
| F15E6.3 | fbf-1 | F15E6.3.1 | H12I13.4.1 | RRM-type RNA binding protein. | Fem-3 mRNA-binding factor 1; Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression, possibly by directly binding to two sites within the 3'-UTR of gld-3 isoform b. In association with the cye-1/cdk-2 complex, negatively regulates gld-1 expression in the distal germline cells of the mitotic zone. By binding to the 3'-UTR, repres [...] | 0.741 |
| F15E6.3 | fbf-2 | F15E6.3.1 | F21H12.5.1 | RRM-type RNA binding protein. | Fem-3 mRNA-binding factor 2; Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. By binding to the 3'-UTR, represses phosphatase lip-1 expression in the distal part of the germline mitotic zone. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform b 3'-UTR. Suppresses germline tumor formation by preventing the d [...] | 0.729 |
| F15E6.3 | fem-3 | F15E6.3.1 | C01F6.4a.1 | RRM-type RNA binding protein. | Sex-determination protein fem-3; Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite) animals, it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2. Together with fem-2 associates with the CBC(fem-1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tra-1. | 0.590 |
| F15E6.3 | fog-1 | F15E6.3.1 | Y54E10A.4b.1 | RRM-type RNA binding protein. | RRM domain-containing protein. | 0.662 |
| F15E6.3 | fog-3 | F15E6.3.1 | C03C11.2.1 | RRM-type RNA binding protein. | Anti_prolifrtn domain-containing protein. | 0.693 |
| F15E6.3 | gld-1 | F15E6.3.1 | T23G11.3.1 | RRM-type RNA binding protein. | Female germline-specific tumor suppressor gld-1; RNA-binding protein which recognizes the 5'-UACUCAU-3' RNA consensus sequence. Binds sequences in both the 5'coding and the 3'-UTR region of rme-2 mRNA. Binds sequences in the 3'-UTR region of cye-1 mRNA. Binds to cyb-2.1, cyb-2.2 and cyb-3 mRNA. Binds sequences in the 3'-UTR region of tra-2 mRNA. Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pa [...] | 0.854 |
| F15E6.3 | gld-3 | F15E6.3.1 | T07F8.3a.1 | RRM-type RNA binding protein. | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | 0.663 |
| car-1 | F15E6.3 | Y18D10A.17.1 | F15E6.3.1 | Cytokinesis, Apoptosis, RNA-associated. | RRM-type RNA binding protein. | 0.663 |
| car-1 | cgh-1 | Y18D10A.17.1 | C07H6.5.1 | Cytokinesis, Apoptosis, RNA-associated. | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.999 |
| car-1 | cpb-3 | Y18D10A.17.1 | B0414.5.1 | Cytokinesis, Apoptosis, RNA-associated. | Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis. | 0.870 |
| car-1 | fog-1 | Y18D10A.17.1 | Y54E10A.4b.1 | Cytokinesis, Apoptosis, RNA-associated. | RRM domain-containing protein. | 0.608 |
| car-1 | gld-1 | Y18D10A.17.1 | T23G11.3.1 | Cytokinesis, Apoptosis, RNA-associated. | Female germline-specific tumor suppressor gld-1; RNA-binding protein which recognizes the 5'-UACUCAU-3' RNA consensus sequence. Binds sequences in both the 5'coding and the 3'-UTR region of rme-2 mRNA. Binds sequences in the 3'-UTR region of cye-1 mRNA. Binds to cyb-2.1, cyb-2.2 and cyb-3 mRNA. Binds sequences in the 3'-UTR region of tra-2 mRNA. Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pa [...] | 0.895 |
| car-1 | ifet-1 | Y18D10A.17.1 | F56F3.1.1 | Cytokinesis, Apoptosis, RNA-associated. | Translational repressor ifet-1; Involved in translational repression of multiple mRNAs in the distal gonad. Recruited to the 3' untranslated region (UTR) of zif-1 by oma-1 and is required for translational repression of zif-1. May also be involved in translational repression of mei-1 through recruitment to the mei-1 3' UTR by oma-1. Required for oogenesis but not spermatogenesis, for P granule formation and for the localization of car-1 and cgh-1 to P granules. Required for normal spindle orientation in early embryos. | 0.998 |
| car-1 | ima-3 | Y18D10A.17.1 | F32E10.4.1 | Cytokinesis, Apoptosis, RNA-associated. | Importin subunit alpha-3; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs. Necessary for correct nucleoporin localization within the germline. Belongs to the importin alpha family. | 0.418 |
| car-1 | larp-1 | Y18D10A.17.1 | R144.7b.1 | Cytokinesis, Apoptosis, RNA-associated. | La-related protein 1; RNA-binding protein that promotes oogenesis by repressing fem-3 expression during germline development. Binds poly-U and poly-G stretches of RNA in vitro. Regulates target RNAs expression either by regulating their stability or translation. | 0.476 |
| car-1 | rme-2 | Y18D10A.17.1 | T11F8.3a.1 | Cytokinesis, Apoptosis, RNA-associated. | Receptor Mediated Endocytosis. | 0.477 |
| cgh-1 | F15E6.3 | C07H6.5.1 | F15E6.3.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | RRM-type RNA binding protein. | 0.775 |
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