STRINGSTRING
pgk-1 pgk-1 dcap-1 dcap-1 inf-1 inf-1 lsm-1 lsm-1 pyk-1 pyk-1 C37C3.2 C37C3.2 act-5 act-5 xrn-1 xrn-1 Y44E3A.6 Y44E3A.6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgk-1Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
dcap-1mRNA_decap_C domain-containing protein. (332 aa)
inf-1Eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon; Belongs to the DEAD box helicase family. eIF4A subfamily. (402 aa)
lsm-1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (125 aa)
pyk-1Pyruvate kinase; Belongs to the pyruvate kinase family. (913 aa)
C37C3.2Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). (436 aa)
act-5ACTin. (375 aa)
xrn-15'-3' exoribonuclease 1. (1591 aa)
Y44E3A.6FHA domain-containing protein. (843 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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