node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ada-2 | gei-8 | F32A5.1a.1 | C14B9.6a.3 | SANT domain-containing protein. | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. | 0.972 |
ada-2 | prde-1 | F32A5.1a.1 | F21A3.5.1 | SANT domain-containing protein. | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | 0.692 |
ada-2 | snpc-4 | F32A5.1a.1 | F32H2.1a.1 | SANT domain-containing protein. | snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs. | 0.748 |
ada-2 | tbp-1 | F32A5.1a.1 | T20B12.2.1 | SANT domain-containing protein. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.446 |
ada-2 | tofu-4 | F32A5.1a.1 | F57C9.7.1 | SANT domain-containing protein. | Twenty One u-rna (21U-RNA) biogenesis Fouled Up. | 0.691 |
ada-2 | tofu-5 | F32A5.1a.1 | W01A8.5.2 | SANT domain-containing protein. | Twenty One u-rna (21U-RNA) biogenesis Fouled Up. | 0.699 |
gei-8 | ada-2 | C14B9.6a.3 | F32A5.1a.1 | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. | SANT domain-containing protein. | 0.972 |
gei-8 | set-16 | C14B9.6a.3 | T12D8.1.1 | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. | Histone-lysine N-methyltransferase. | 0.430 |
gei-8 | tbp-1 | C14B9.6a.3 | T20B12.2.1 | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.935 |
gei-8 | tofu-5 | C14B9.6a.3 | W01A8.5.2 | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. | Twenty One u-rna (21U-RNA) biogenesis Fouled Up. | 0.422 |
pid-1 | prde-1 | F18A1.8.1 | F21A3.5.1 | 21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | 0.746 |
pid-1 | snpc-4 | F18A1.8.1 | F32H2.1a.1 | 21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. | snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs. | 0.564 |
pid-1 | tofu-4 | F18A1.8.1 | F57C9.7.1 | 21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. | Twenty One u-rna (21U-RNA) biogenesis Fouled Up. | 0.714 |
pid-1 | tofu-5 | F18A1.8.1 | W01A8.5.2 | 21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. | Twenty One u-rna (21U-RNA) biogenesis Fouled Up. | 0.626 |
prde-1 | ada-2 | F21A3.5.1 | F32A5.1a.1 | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | SANT domain-containing protein. | 0.692 |
prde-1 | pid-1 | F21A3.5.1 | F18A1.8.1 | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | 21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. | 0.746 |
prde-1 | set-16 | F21A3.5.1 | T12D8.1.1 | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | Histone-lysine N-methyltransferase. | 0.429 |
prde-1 | set-6 | F21A3.5.1 | C49F5.2.1 | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | SET domain-containing protein. | 0.486 |
prde-1 | snpc-4 | F21A3.5.1 | F32H2.1a.1 | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs. | 0.967 |
prde-1 | tofu-4 | F21A3.5.1 | F57C9.7.1 | piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. | Twenty One u-rna (21U-RNA) biogenesis Fouled Up. | 0.988 |