STRINGSTRING
ada-2 ada-2 trf-2 trf-2 tofu-5 tofu-5 tbp-1 tbp-1 set-16 set-16 ulp-5 ulp-5 tofu-4 tofu-4 gei-8 gei-8 unc-130 unc-130 set-6 set-6 pid-1 pid-1 prde-1 prde-1 snpc-4 snpc-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ada-2SANT domain-containing protein. (596 aa)
trf-2MATH domain-containing protein. (335 aa)
tofu-5Twenty One u-rna (21U-RNA) biogenesis Fouled Up. (311 aa)
tbp-1TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (340 aa)
set-16Histone-lysine N-methyltransferase. (2475 aa)
ulp-5ULP_PROTEASE domain-containing protein. (311 aa)
tofu-4Twenty One u-rna (21U-RNA) biogenesis Fouled Up. (412 aa)
gei-8Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. (1778 aa)
unc-130Fork-head domain-containing protein. (333 aa)
set-6SET domain-containing protein. (708 aa)
pid-121U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. (169 aa)
prde-1piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility. (526 aa)
snpc-4snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs. (944 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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