STRINGSTRING
his-60 his-60 his-31 his-31 his-64 his-64 cec-4 cec-4 his-5 his-5 his-56 his-56 his-14 his-14 his-10 his-10 his-26 his-26 his-67 his-67 his-1 his-1 his-28 his-28 his-18 his-18 his-46 his-46 his-38 his-38 his-37 his-37 his-50 his-50
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
his-60Histone H4. (103 aa)
his-31Histone H4. (103 aa)
his-64Histone H4. (103 aa)
cec-4Chromo domain-containing protein cec-4; Chromatin anchor protein which binds to methylated lysine residues on histone H3, thereby recruiting heterochromatin to the nuclear periphery. May be required for the correct positioning of chromatin and nucleoli in embryos. (270 aa)
his-5Histone H4. (103 aa)
his-56Histone H4. (103 aa)
his-14Histone H4. (103 aa)
his-10Histone H4. (103 aa)
his-26Histone H4. (103 aa)
his-67Histone H4. (103 aa)
his-1Histone H4. (103 aa)
his-28Histone H4. (103 aa)
his-18Histone H4. (103 aa)
his-46Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
his-38Histone H4. (103 aa)
his-37Histone H4. (103 aa)
his-50Histone H4. (103 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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