Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C46A5.4 | T06D8.10 | C46A5.4.1 | T06D8.10.1 | Uncharacterized protein. | Uncharacterized protein. | 0.699 |
| C46A5.4 | act-5 | C46A5.4.1 | T25C8.2.2 | Uncharacterized protein. | ACTin. | 0.898 |
| C46A5.4 | pxn-1 | C46A5.4.1 | ZK994.3.1 | Uncharacterized protein. | Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. | 0.705 |
| C46A5.4 | pxn-2 | C46A5.4.1 | K09C8.5.1 | Uncharacterized protein. | PeroXidasiN (Drosophila peroxidase) homolog. | 0.709 |
| C46F11.6 | ned-8 | C46F11.6.1 | F45H11.2.1 | Ubiquitin-like protein. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.890 |
| C46F11.6 | rfl-1 | C46F11.6.1 | F11H8.1.2 | Ubiquitin-like protein. | NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric rfl-1 (uba-3)-ula-1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-uba-3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of ubc-12 (By similarity). Required for cytokinesis and mitotic spindle orientation during early embryogenesis. | 0.456 |
| C46F11.6 | smo-1 | C46F11.6.1 | K12C11.2.1 | Ubiquitin-like protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.806 |
| T06D8.10 | C46A5.4 | T06D8.10.1 | C46A5.4.1 | Uncharacterized protein. | Uncharacterized protein. | 0.699 |
| T06D8.10 | act-5 | T06D8.10.1 | T25C8.2.2 | Uncharacterized protein. | ACTin. | 0.898 |
| T06D8.10 | pxn-1 | T06D8.10.1 | ZK994.3.1 | Uncharacterized protein. | Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. | 0.707 |
| T06D8.10 | pxn-2 | T06D8.10.1 | K09C8.5.1 | Uncharacterized protein. | PeroXidasiN (Drosophila peroxidase) homolog. | 0.711 |
| act-5 | C46A5.4 | T25C8.2.2 | C46A5.4.1 | ACTin. | Uncharacterized protein. | 0.898 |
| act-5 | T06D8.10 | T25C8.2.2 | T06D8.10.1 | ACTin. | Uncharacterized protein. | 0.898 |
| act-5 | cul-1 | T25C8.2.2 | D2045.6.1 | ACTin. | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | 0.490 |
| act-5 | cul-3 | T25C8.2.2 | Y108G3AL.1a.3 | ACTin. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.805 |
| act-5 | ned-8 | T25C8.2.2 | F45H11.2.1 | ACTin. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.442 |
| act-5 | pxn-1 | T25C8.2.2 | ZK994.3.1 | ACTin. | Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. | 0.918 |
| act-5 | pxn-2 | T25C8.2.2 | K09C8.5.1 | ACTin. | PeroXidasiN (Drosophila peroxidase) homolog. | 0.916 |
| act-5 | smo-1 | T25C8.2.2 | K12C11.2.1 | ACTin. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.765 |
| cdt-1 | csn-5 | Y54E10A.15.1 | B0547.1.1 | CDT1 domain-containing protein. | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of [...] | 0.469 |
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