15 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tcer-1	WW domain-containing protein. (914 aa)
	acs-22	Fatty Acid CoA Synthetase family. (655 aa)
	fat-7	Delta(9)-fatty-acid desaturase fat-7; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA, heptadecanyol-CoA, and palmitoyl-CoA. (338 aa)
	fasn-1	Carrier domain-containing protein. (2613 aa)
	mlcd-1	MaLonyl CoA Decarboxylase. (442 aa)
	dgat-2	Acyl-CoA:DiacylGlycerol AcylTransferase. (345 aa)
	nhr-80	Nuclear Hormone Receptor family. (504 aa)
	mboa-2	O-acyltransferase. (498 aa)
	lipl-4	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (411 aa)
	K07B1.4	Uncharacterized protein. (349 aa)
	nhr-49	Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. (501 aa)
	daf-16	Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] (541 aa)
	fat-6	Delta(9)-fatty-acid desaturase fat-6; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. Belongs to the fatty acid desaturase type 1 family. (339 aa)
	pod-2	Uncharacterized protein. (2165 aa)
	Y53G8B.2	Uncharacterized protein. (340 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K07B1.4	Y53G8B.2	K07B1.4a.1	Y53G8B.2.1	Uncharacterized protein.	Uncharacterized protein.	0.449
K07B1.4	acs-22	K07B1.4a.1	D1009.1a.1	Uncharacterized protein.	Fatty Acid CoA Synthetase family.	0.775
K07B1.4	dgat-2	K07B1.4a.1	F59A1.10.1	Uncharacterized protein.	Acyl-CoA:DiacylGlycerol AcylTransferase.	0.448
K07B1.4	fasn-1	K07B1.4a.1	F32H2.5.1	Uncharacterized protein.	Carrier domain-containing protein.	0.567
K07B1.4	mboa-2	K07B1.4a.1	H19N07.4a.2	Uncharacterized protein.	O-acyltransferase.	0.988
K07B1.4	mlcd-1	K07B1.4a.1	F35G12.1a.1	Uncharacterized protein.	MaLonyl CoA Decarboxylase.	0.812
K07B1.4	pod-2	K07B1.4a.1	W09B6.1c.1	Uncharacterized protein.	Uncharacterized protein.	0.579
K07B1.4	tcer-1	K07B1.4a.1	ZK1127.9a.1	Uncharacterized protein.	WW domain-containing protein.	0.697
Y53G8B.2	K07B1.4	Y53G8B.2.1	K07B1.4a.1	Uncharacterized protein.	Uncharacterized protein.	0.449
Y53G8B.2	acs-22	Y53G8B.2.1	D1009.1a.1	Uncharacterized protein.	Fatty Acid CoA Synthetase family.	0.737
Y53G8B.2	dgat-2	Y53G8B.2.1	F59A1.10.1	Uncharacterized protein.	Acyl-CoA:DiacylGlycerol AcylTransferase.	0.432
Y53G8B.2	fasn-1	Y53G8B.2.1	F32H2.5.1	Uncharacterized protein.	Carrier domain-containing protein.	0.464
Y53G8B.2	mboa-2	Y53G8B.2.1	H19N07.4a.2	Uncharacterized protein.	O-acyltransferase.	0.905
Y53G8B.2	mlcd-1	Y53G8B.2.1	F35G12.1a.1	Uncharacterized protein.	MaLonyl CoA Decarboxylase.	0.697
Y53G8B.2	pod-2	Y53G8B.2.1	W09B6.1c.1	Uncharacterized protein.	Uncharacterized protein.	0.456
acs-22	K07B1.4	D1009.1a.1	K07B1.4a.1	Fatty Acid CoA Synthetase family.	Uncharacterized protein.	0.775
acs-22	Y53G8B.2	D1009.1a.1	Y53G8B.2.1	Fatty Acid CoA Synthetase family.	Uncharacterized protein.	0.737
acs-22	dgat-2	D1009.1a.1	F59A1.10.1	Fatty Acid CoA Synthetase family.	Acyl-CoA:DiacylGlycerol AcylTransferase.	0.887
acs-22	fasn-1	D1009.1a.1	F32H2.5.1	Fatty Acid CoA Synthetase family.	Carrier domain-containing protein.	0.506
acs-22	lipl-4	D1009.1a.1	K04A8.5a.1	Fatty Acid CoA Synthetase family.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.464