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| | col-41 | Col_cuticle_N domain-containing protein. (428 aa) |
| | col-34 | Cuticle collagen 34; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. (299 aa) |
| | ram-2 | Col_cuticle_N domain-containing protein. (306 aa) |
| | dpy-7 | Cuticle collagen dpy-7; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-7 affects the body shape. (318 aa) |
| | dpy-11 | Thioredoxin domain-containing protein. (246 aa) |
| | F49B2.6 | Aminopeptidase. (1082 aa) |
| | noah-2 | NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A). (741 aa) |
| | che-14 | SSD domain-containing protein. (917 aa) |
| | F57F4.4 | Uncharacterized protein. (2090 aa) |
| | cbd-1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. (1319 aa) |
| | let-805 | Myotactin form B. (4450 aa) |
| | egg-6 | Leucine-rich repeat-containing protein egg-6; Required for apical extracellular matrix organization and epithelial junction maintenance. (961 aa) |
| | mup-4 | Transmembrane matrix receptor MUP-4; Required for junctional attachments between hypodermis and muscle, and between the apical epithelial surface and the cuticular matrix. Essential for enclosure of the embryo by the hypodermis, hypodermal integrity, embryo elongation, and maintenance of hypodermal morphology in fully elongated embryos. (2104 aa) |
| | vit-6 | Vitellogenin-6; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Probable). May play a role in cholesterol uptake. May be involved in thermotolerance. (1651 aa) |
| | mua-3 | Transmembrane cell adhesion receptor mua-3; Involved in cell adhesion and required for organ positioning and attachment. At the hypodermal surface, required for attachment of the hypdermermis to the basal cuticle in postembryonic development, possibly through intermediate filaments of the cytoskeleton. (3767 aa) |
| | R03G8.4 | Aminopeptidase. (786 aa) |
| | R03G8.6 | Aminopeptidase. (747 aa) |
| | cut-5 | ZP domain-containing protein. (395 aa) |
| | nphp-4 | NePHronoPhthisis (Human kidney disease) homolog. (1305 aa) |
| | rol-6 | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. (348 aa) |
| | anp-1 | Aminopeptidase. (988 aa) |
| | dpy-2 | Cuticle collagen dpy-2; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-2 affects the body shape. (380 aa) |
| | dpy-10 | Cuticle collagen dpy-10; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. (356 aa) |
| | col-142 | Col_cuticle_N domain-containing protein. (325 aa) |
| | col-141 | Col_cuticle_N domain-containing protein. (314 aa) |
| | ram-5 | ZP domain-containing protein. (711 aa) |
| | act-5 | ACTin. (375 aa) |
| | dbl-1 | TGF_BETA_2 domain-containing protein. (365 aa) |
| | par-6 | Partitioning defective protein 6; Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Regulates mes-1 expression and/or localization pattern during early embryogenesis. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. Plays a role in endosome and Golgi body positioning. Belongs to the PAR6 family. (309 aa) |
| | lec-10 | Galectin. (192 aa) |
| | ule-1 | Uterine Lumin Expressed/locailized. (235 aa) |
| | lpr-3 | LiPocalin-Related protein. (569 aa) |
| | Y42A5A.1 | Aminopeptidase. (1045 aa) |
| | dpy-18 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. (559 aa) |
| | ral-1 | RAL (Ras-related GTPase) homolog. (254 aa) |
| | lec-6 | Galectin. (146 aa) |
| | lon-8 | Protein lon-8; Secreted protein that is involved in larval elongation, early adult growth and male tail development. (162 aa) |
| | ule-5 | Uterine Lumin Expressed/locailized. (181 aa) |
| | lpr-1 | LiPocalin-Related protein. (275 aa) |
| | Y67D8C.9 | Uncharacterized protein. (1144 aa) |
| | pod-1 | Uncharacterized protein. (1136 aa) |
| | abu-14 | Activated in Blocked Unfolded protein response. (373 aa) |
| | lap-1 | Leucine aminopeptidase 1; Probably acts as a digestive enzyme. (491 aa) |
| | fbn-1 | FiBrilliN homolog. (2781 aa) |
| | nas-6 | Zinc metalloproteinase nas-6; Metalloprotease. (344 aa) |
| | cpg-2 | Chondroitin proteoglycan-2; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. (524 aa) |
| | sqt-1 | Cuticle collagen sqt-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This is a collagen critical for organismal morphogenesis. Mutations in sqt-1 can lengthen, shorten, or helically twist the entire animal. (324 aa) |
| | adt-1 | A disintegrin and metalloproteinase with thrombospondin motifs adt-1; Plays a role in ray morphogenesis in the male tail, probably by remodeling the extracellular matrix (ECM) in the cuticle. (1461 aa) |
| | nas-7 | Zinc metalloproteinase nas-7; Metalloprotease. (382 aa) |
| | cpg-1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. (584 aa) |
| | mlt-10 | Uncharacterized protein. (690 aa) |
| | bli-1 | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. (948 aa) |
| | tmem-131 | TMEM131_like domain-containing protein. (1831 aa) |
| | let-653 | Protein let-653; Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development. (812 aa) |
| | noah-1 | NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A). (1052 aa) |
| | dyf-7 | Protein dyf-7; Required for permeability of amphid and phasmid neurons to external dyes, chemotaxis to ammonium chloride, avoidance of high osmotic stimuli, male mating and dauer formation. Along with dex-1, enables neurite growth and maintenance by anchoring amphid dendritic tips during neuron cell body migration in embryonic and larval development. (446 aa) |
| | perm-2 | PERMeable eggshell. (203 aa) |
| | perm-4 | PERMeable eggshell. (331 aa) |
| | let-4 | Leucine-rich repeat-containing protein let-4; Required for apical extracellular matrix organization and epithelial junction maintenance. (773 aa) |
| | sym-1 | SYM-1 protein. (680 aa) |
| | ilys-3 | Invertebrate-type lysozyme 3; Has bacteriolytic activity against Gram-positive bacteria. Plays a role in defense against bacterial pathogens. Involved in pharyngeal grinder function by enabling proper lysis of ingested bacteria; Belongs to the glycosyl hydrolase 22 family. Type-I lysozyme subfamily. (139 aa) |
| | cut-1 | Cuticlin-1; Component of the cuticles. It forms a ribbon approximately 2 microns wide running along the lateral lines underneath the alae. Contributes to the formation of extracellular envelopes protecting the organism from the environment. (424 aa) |
| | dex-1 | Dendrite extension defective protein 1; Along with dyf-7, enables neurite growth and maintenance by anchoring amphid dendritic tips during neuron cell body migration in embryonic and larval development. (1137 aa) |
| | cut-4 | ZP domain-containing protein. (507 aa) |
| | dpy-3 | Col_cuticle_N domain-containing protein. (302 aa) |
| | ceh-60 | Homeobox domain-containing protein. (360 aa) |
| | cut-3 | ZP domain-containing protein. (389 aa) |
| | sqt-3 | Cuticle collagen 1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. (301 aa) |
| | dpy-5 | Cuticle collagen dpy-5; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. (284 aa) |
| | acs-20 | Fatty Acid CoA Synthetase family. (684 aa) |
| | dpy-13 | Cuticle collagen dpy-13; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-13 affects the body shape. (302 aa) |
| | daf-6 | SSD domain-containing protein. (913 aa) |
| | cpz-1 | Cathepsin Z-1; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. Probably, required for the degradation of the old cuticle. Belongs to the peptidase C1 family. (306 aa) |
| | fasn-1 | Carrier domain-containing protein. (2613 aa) |
| | vha-5 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa) |
