node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cyn-2 | cyp-35A1 | ZK520.5.1 | C03G6.14.1 | Peptidyl-prolyl cis-trans isomerase 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.533 |
cyn-2 | rla-1 | ZK520.5.1 | Y37E3.7.3 | Peptidyl-prolyl cis-trans isomerase 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 60S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. | 0.424 |
cyp-35A1 | cyn-2 | C03G6.14.1 | ZK520.5.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | Peptidyl-prolyl cis-trans isomerase 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.533 |
cyp-35A1 | cyp-35A5 | C03G6.14.1 | K07C6.5.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.405 |
cyp-35A1 | irg-6 | C03G6.14.1 | C32H11.1a.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CUB_2 domain-containing protein. | 0.480 |
cyp-35A2 | cyp-35A3 | C03G6.15.1 | K09D9.2.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.565 |
cyp-35A2 | cyp-35A5 | C03G6.15.1 | K07C6.5.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.418 |
cyp-35A3 | cyp-35A2 | K09D9.2.1 | C03G6.15.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.565 |
cyp-35A3 | cyp-35A5 | K09D9.2.1 | K07C6.5.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.476 |
cyp-35A5 | cyp-35A1 | K07C6.5.1 | C03G6.14.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.405 |
cyp-35A5 | cyp-35A2 | K07C6.5.1 | C03G6.15.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.418 |
cyp-35A5 | cyp-35A3 | K07C6.5.1 | K09D9.2.1 | CYtochrome P450 family; Belongs to the cytochrome P450 family. | CYtochrome P450 family; Belongs to the cytochrome P450 family. | 0.476 |
daf-16 | fat-5 | R13H8.1h.1 | W06D12.3.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Delta(9)-fatty-acid desaturase fat-5; Delta(9)-fatty-acid desaturase that acts preferentially on palmitoyl-CoA. Also acts on pentadecanoyl-coA and myristoyl-CoA. | 0.660 |
daf-16 | irg-4 | R13H8.1h.1 | F08G5.6.2 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | CUB_2 domain-containing protein. | 0.463 |
daf-16 | irg-5 | R13H8.1h.1 | F35E12.5.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | CUB_2 domain-containing protein. | 0.413 |
fat-5 | daf-16 | W06D12.3.1 | R13H8.1h.1 | Delta(9)-fatty-acid desaturase fat-5; Delta(9)-fatty-acid desaturase that acts preferentially on palmitoyl-CoA. Also acts on pentadecanoyl-coA and myristoyl-CoA. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.660 |
irg-4 | daf-16 | F08G5.6.2 | R13H8.1h.1 | CUB_2 domain-containing protein. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.463 |
irg-4 | irg-5 | F08G5.6.2 | F35E12.5.1 | CUB_2 domain-containing protein. | CUB_2 domain-containing protein. | 0.937 |
irg-4 | irg-6 | F08G5.6.2 | C32H11.1a.1 | CUB_2 domain-containing protein. | CUB_2 domain-containing protein. | 0.815 |
irg-5 | daf-16 | F35E12.5.1 | R13H8.1h.1 | CUB_2 domain-containing protein. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.413 |