Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| act-5 | mig-2 | T25C8.2.2 | C35C5.4a.1 | ACTin. | Rac-like GTPase. | 0.752 |
| act-5 | ost-1 | T25C8.2.2 | C44B12.2a.1 | ACTin. | SPARC; Has a high affinity for collagen. Affects nematode body morphology and mobility. Essential for C.elegans development and muscle function. The cysteine-rich region could have protease inhibitory activity or may provide the framework for a protein binding module. Probable role in skeletal morphogenesis; Belongs to the SPARC family. | 0.528 |
| act-5 | rac-2 | T25C8.2.2 | K03D3.10.1 | ACTin. | Ras-related protein rac-2; During gonad morphogenesis, plays a role in distal tip cell (DTC)-mediated guidance of gonad elongation. | 0.845 |
| act-5 | snt-3 | T25C8.2.2 | Y75B7AL.3.1 | ACTin. | SyNapTotagmin. | 0.700 |
| act-5 | snt-4 | T25C8.2.2 | T23H2.2.1 | ACTin. | SyNapTotagmin. | 0.715 |
| act-5 | snt-5 | T25C8.2.2 | R12A1.2a.1 | ACTin. | SyNapTotagmin. | 0.700 |
| act-5 | snt-6 | T25C8.2.2 | C08G5.4a.1 | ACTin. | C2 domain-containing protein. | 0.741 |
| act-5 | snt-7 | T25C8.2.2 | T10B10.5.1 | ACTin. | C2 domain-containing protein. | 0.699 |
| act-5 | sph-1 | T25C8.2.2 | F42G8.11.1 | ACTin. | MARVEL domain-containing protein. | 0.749 |
| gcy-8 | kcc-3 | C49H3.1.1 | K02A2.3b.1 | Receptor-type guanylate cyclase gcy-8; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients. Maintains the microvilli receptive ending morphology of the AFD thermosensory neurons by regulating cGMP levels downstream of kcc-3. cGMP levels antagonize the actin cytoskeleton regulator wsp-1. | Potassium/chloride cotransporter 3; Probable potassium/chloride cotransporter that functions in the amphid sheath glial cells to regulate thermotaxis behavior. By maintaining chloride homeostasis, negatively regulates guanylate cyclase gcy-8 in the thermosensory AFD neurons and thereby controls the microvilli receptive ending morphology of the AFD neurons and thermotaxis. Modulates the temperature-evoked neuronal activity of the AFD neurons such as calcium responses to temperature gradients. Might also play a role in the chemotaxis behavior mediated by the sensory neurons AWA and AWC. | 0.758 |
| gpn-1 | ost-1 | F59D12.4.1 | C44B12.2a.1 | GlyPicaN; Belongs to the glypican family. | SPARC; Has a high affinity for collagen. Affects nematode body morphology and mobility. Essential for C.elegans development and muscle function. The cysteine-rich region could have protease inhibitory activity or may provide the framework for a protein binding module. Probable role in skeletal morphogenesis; Belongs to the SPARC family. | 0.633 |
| kcc-3 | gcy-8 | K02A2.3b.1 | C49H3.1.1 | Potassium/chloride cotransporter 3; Probable potassium/chloride cotransporter that functions in the amphid sheath glial cells to regulate thermotaxis behavior. By maintaining chloride homeostasis, negatively regulates guanylate cyclase gcy-8 in the thermosensory AFD neurons and thereby controls the microvilli receptive ending morphology of the AFD neurons and thermotaxis. Modulates the temperature-evoked neuronal activity of the AFD neurons such as calcium responses to temperature gradients. Might also play a role in the chemotaxis behavior mediated by the sensory neurons AWA and AWC. | Receptor-type guanylate cyclase gcy-8; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients. Maintains the microvilli receptive ending morphology of the AFD thermosensory neurons by regulating cGMP levels downstream of kcc-3. cGMP levels antagonize the actin cytoskeleton regulator wsp-1. | 0.758 |
| mig-2 | act-5 | C35C5.4a.1 | T25C8.2.2 | Rac-like GTPase. | ACTin. | 0.752 |
| mig-2 | rac-2 | C35C5.4a.1 | K03D3.10.1 | Rac-like GTPase. | Ras-related protein rac-2; During gonad morphogenesis, plays a role in distal tip cell (DTC)-mediated guidance of gonad elongation. | 0.905 |
| nlg-1 | snt-3 | C40C9.5e.1 | Y75B7AL.3.1 | Neuroligin-1; Probable neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins (By similarity). Plays a role in the clustering of the GABA(A) receptor unc-49 at postsynaptic sites in neuromuscular junctions (NMJs) via the interaction with madd-4 and neurexin nrx-1 and is thereby required for normal GABAergic synaptic transmission. Belongs to the type-B carboxylesterase/lipase family. | SyNapTotagmin. | 0.489 |
| nlg-1 | snt-4 | C40C9.5e.1 | T23H2.2.1 | Neuroligin-1; Probable neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins (By similarity). Plays a role in the clustering of the GABA(A) receptor unc-49 at postsynaptic sites in neuromuscular junctions (NMJs) via the interaction with madd-4 and neurexin nrx-1 and is thereby required for normal GABAergic synaptic transmission. Belongs to the type-B carboxylesterase/lipase family. | SyNapTotagmin. | 0.437 |
| nlg-1 | snt-5 | C40C9.5e.1 | R12A1.2a.1 | Neuroligin-1; Probable neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins (By similarity). Plays a role in the clustering of the GABA(A) receptor unc-49 at postsynaptic sites in neuromuscular junctions (NMJs) via the interaction with madd-4 and neurexin nrx-1 and is thereby required for normal GABAergic synaptic transmission. Belongs to the type-B carboxylesterase/lipase family. | SyNapTotagmin. | 0.477 |
| nlg-1 | snt-6 | C40C9.5e.1 | C08G5.4a.1 | Neuroligin-1; Probable neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins (By similarity). Plays a role in the clustering of the GABA(A) receptor unc-49 at postsynaptic sites in neuromuscular junctions (NMJs) via the interaction with madd-4 and neurexin nrx-1 and is thereby required for normal GABAergic synaptic transmission. Belongs to the type-B carboxylesterase/lipase family. | C2 domain-containing protein. | 0.554 |
| nlg-1 | snt-7 | C40C9.5e.1 | T10B10.5.1 | Neuroligin-1; Probable neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins (By similarity). Plays a role in the clustering of the GABA(A) receptor unc-49 at postsynaptic sites in neuromuscular junctions (NMJs) via the interaction with madd-4 and neurexin nrx-1 and is thereby required for normal GABAergic synaptic transmission. Belongs to the type-B carboxylesterase/lipase family. | C2 domain-containing protein. | 0.485 |
| nlg-1 | sph-1 | C40C9.5e.1 | F42G8.11.1 | Neuroligin-1; Probable neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins (By similarity). Plays a role in the clustering of the GABA(A) receptor unc-49 at postsynaptic sites in neuromuscular junctions (NMJs) via the interaction with madd-4 and neurexin nrx-1 and is thereby required for normal GABAergic synaptic transmission. Belongs to the type-B carboxylesterase/lipase family. | MARVEL domain-containing protein. | 0.545 |
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