Twenty-One u (U) antagoniST.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Twenty-One u (U) antagoniST.

Uncharacterized protein.

Twenty-One u (U) antagoniST.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Twenty-One u (U) antagoniST.

Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of PIWI-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) which are classes of regulatory RNAs that are involved in gene silencing in endogenous RNA interference (RNAi) pathways. Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries (Probable). Methylates and stabilizes 26G-siRNAs (a class of 26 nucleotide siRNAs that possess a monophosphorylated guanine residue at the 5'-end) when t [...]

Twenty-One u (U) antagoniST.

Eukaryotic translation initiation factor 4E-3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. All 5 eIF4E proteins bind monomethyl cap structures. Only ife-1, ife-2 and ife-5 bind trimethyl cap structures which result from trans-splicing. Translation of trimethyl cap structure mRNAs may be regulated by intracellular redox state; disulfide bonds change the width and depth of the cap-binding cavity determining selectivit [...]

Twenty-One u (U) antagoniST.

3'-5' exoribonuclease parn-1; Involved in transcriptome surveillance. Required for piwi- interacting RNAs (piRNAs) 3'-end trimming, which is important for both fertility and piRNA-directed gene silencing. Has 3' to 5' exonuclease activity in vitro.

Twenty-One u (U) antagoniST.

21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing.

Twenty-One u (U) antagoniST.

piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility.

Twenty-One u (U) antagoniST.

Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...]

Twenty-One u (U) antagoniST.

snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs.

Twenty-One u (U) antagoniST.

Twenty One u-rna (21U-RNA) biogenesis Fouled Up.

Twenty-One u (U) antagoniST.

Embryonic developmental protein tofu-6; Required maternally for early embryonic cell divisions. May have a role in DNA replication.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Twenty-One u (U) antagoniST.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Uncharacterized protein.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of PIWI-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) which are classes of regulatory RNAs that are involved in gene silencing in endogenous RNA interference (RNAi) pathways. Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries (Probable). Methylates and stabilizes 26G-siRNAs (a class of 26 nucleotide siRNAs that possess a monophosphorylated guanine residue at the 5'-end) when t [...]

Enhancer of rudimentary homolog; May have a role in the cell cycle.

Eukaryotic translation initiation factor 4E-3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. All 5 eIF4E proteins bind monomethyl cap structures. Only ife-1, ife-2 and ife-5 bind trimethyl cap structures which result from trans-splicing. Translation of trimethyl cap structure mRNAs may be regulated by intracellular redox state; disulfide bonds change the width and depth of the cap-binding cavity determining selectivit [...]

Enhancer of rudimentary homolog; May have a role in the cell cycle.

3'-5' exoribonuclease parn-1; Involved in transcriptome surveillance. Required for piwi- interacting RNAs (piRNAs) 3'-end trimming, which is important for both fertility and piRNA-directed gene silencing. Has 3' to 5' exonuclease activity in vitro.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

21U-RNA biogenesis factor pid-1; Plays a role in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing.

Enhancer of rudimentary homolog; May have a role in the cell cycle.

piRNA biogenesis factor prde-1; Nuclear factor required for the production of piwi- interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility.