Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZK970.8 | act-5 | ZK970.8.1 | T25C8.2.2 | Uncharacterized protein. | ACTin. | 0.912 |
| ZK970.8 | cdc-42 | ZK970.8.1 | R07G3.1.1 | Uncharacterized protein. | Cell division control protein 42 homolog; Plays an essential role in spindle orientation and organizing cellular and embryonic polarity by controlling the localization and activity of PAR (partitioning-defective) proteins. Required for maintaining the asymmetric cortical localization of the anterior complex proteins par-3 and par-6, the posterior cortical protein par-2, and pkc-3. Involved in hypodermal cell fusion, together with pak-1 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. During gonad morphogenesis, plays a role in dista [...] | 0.927 |
| ZK970.8 | deb-1 | ZK970.8.1 | ZC477.9d.1 | Uncharacterized protein. | Vinculin; Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane. Involved in ovulation. | 0.408 |
| ZK970.8 | dyn-1 | ZK970.8.1 | C02C6.1b.1 | Uncharacterized protein. | Dynamin; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). Required for coelomocyte endocytosis. Involved in apoptotic cell phagocytosis. Required for recruitment of phosphatidylinositol 3- kinase piki-1 to phagosomes. May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes. Required for embryonic and larval development. Belongs to the TRAFAC class dynamin-like GTPase supe [...] | 0.724 |
| ZK970.8 | eea-1 | ZK970.8.1 | T10G3.5a.1 | Uncharacterized protein. | FYVE-type domain-containing protein. | 0.497 |
| ZK970.8 | mlc-6 | ZK970.8.1 | K04C1.4.1 | Uncharacterized protein. | Myosin Light Chain. | 0.473 |
| ZK970.8 | mlc-7 | ZK970.8.1 | K08E3.10.1 | Uncharacterized protein. | Myosin Light Chain. | 0.498 |
| ZK970.8 | pak-1 | ZK970.8.1 | C09B8.7a.1 | Uncharacterized protein. | Serine/threonine-protein kinase pak-1; Required for hypodermal cell fusion, together with cdc-42 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. Plays a redundant role with max-2 in dorsal axonal guidance in ventral cord commissural motoneurons and in P neuroblast migration. Acts probably downstream of Rho GTPases mig-2 and ced-10 to regulate these 2 processes. Involved in orientating axonal growth of HSN neurons. During gonad morphogenesis and probably in association with pix-1 and git-1, involved in the migration of distal tip ce [...] | 0.583 |
| ZK970.8 | pxl-1 | ZK970.8.1 | C28H8.6a.1 | Uncharacterized protein. | Paxillin homolog 1; Required for myofilament organization of the pharyngeal sarcomeres and for pharyngeal muscle contractions and hence for pharyngeal pumping. Together with lin-8, might be required for myofilament organization in the body wall muscles ; Belongs to the paxillin family. | 0.698 |
| ZK970.8 | rho-1 | ZK970.8.1 | Y51H4A.3a.1 | Uncharacterized protein. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.943 |
| ZK970.8 | unc-60 | ZK970.8.1 | C38C3.5.1 | Uncharacterized protein. | Actin-depolymerizing factor 2, isoform c; Depolymerizes growing actin filaments in muscle cells; required for the assembly of actin filaments into the functional contractile myofilament lattice of muscle. Belongs to the actin-binding proteins ADF family. | 0.436 |
| act-5 | ZK970.8 | T25C8.2.2 | ZK970.8.1 | ACTin. | Uncharacterized protein. | 0.912 |
| act-5 | cdc-42 | T25C8.2.2 | R07G3.1.1 | ACTin. | Cell division control protein 42 homolog; Plays an essential role in spindle orientation and organizing cellular and embryonic polarity by controlling the localization and activity of PAR (partitioning-defective) proteins. Required for maintaining the asymmetric cortical localization of the anterior complex proteins par-3 and par-6, the posterior cortical protein par-2, and pkc-3. Involved in hypodermal cell fusion, together with pak-1 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. During gonad morphogenesis, plays a role in dista [...] | 0.976 |
| act-5 | cpn-3 | T25C8.2.2 | F28H1.2.1 | ACTin. | Calponin-homology (CH) domain-containing protein. | 0.986 |
| act-5 | cpn-4 | T25C8.2.2 | F49D11.8.1 | ACTin. | Calponin-homology (CH) domain-containing protein. | 0.987 |
| act-5 | deb-1 | T25C8.2.2 | ZC477.9d.1 | ACTin. | Vinculin; Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane. Involved in ovulation. | 0.998 |
| act-5 | dyn-1 | T25C8.2.2 | C02C6.1b.1 | ACTin. | Dynamin; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). Required for coelomocyte endocytosis. Involved in apoptotic cell phagocytosis. Required for recruitment of phosphatidylinositol 3- kinase piki-1 to phagosomes. May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes. Required for embryonic and larval development. Belongs to the TRAFAC class dynamin-like GTPase supe [...] | 0.966 |
| act-5 | eea-1 | T25C8.2.2 | T10G3.5a.1 | ACTin. | FYVE-type domain-containing protein. | 0.743 |
| act-5 | gsnl-1 | T25C8.2.2 | K06A4.3.1 | ACTin. | Gelsolin-like protein 1; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). Binds actin but does not nucleate actin polymerization, albeit slows down elongation by blocking the barbed ends. By promoting actin depolymerization, required for the elimination of presynaptic components downstream of the egl-1, ced-4 and ced-3 apoptotic pathway during larval development. Belongs to the villin/gelsolin family. | 0.997 |
| act-5 | hsp-90 | T25C8.2.2 | C47E8.5.3 | ACTin. | Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] | 0.914 |
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