STRINGSTRING
clp-8 clp-8 ketn-1 ketn-1 daf-16 daf-16 clp-2 clp-2 clp-9 clp-9 act-5 act-5 clp-10 clp-10 clp-4 clp-4 agr-1 agr-1 clp-3 clp-3 clp-6 clp-6 clp-7 clp-7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
clp-8Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (646 aa)
ketn-1KETtiN (Drosophila actin-binding) homolog. (4963 aa)
daf-16Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] (541 aa)
clp-2Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (805 aa)
clp-9Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (718 aa)
act-5ACTin. (375 aa)
clp-10Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (634 aa)
clp-4Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (716 aa)
agr-1AGRin (Synaptic protein) homolog family member. (1473 aa)
clp-3Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (752 aa)
clp-6Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (627 aa)
clp-7Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (778 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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