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pde-3 pde-3 acy-2 acy-2 pde-5 pde-5 acy-3 acy-3 C46A5.4 C46A5.4 acy-1 acy-1 pxn-2 pxn-2 pde-2 pde-2 pde-1 pde-1 T06D8.10 T06D8.10 pxn-1 pxn-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pde-3Probable 3',5'-cyclic phosphodiesterase pde-3. (693 aa)
acy-2Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1080 aa)
pde-5Probable 3',5'-cyclic phosphodiesterase pde-5; Redundantly with pde-1, plays a role in the AFD thermosensory neurons to regulate microvilli receptive ending morphology, possibly by regulating cGMP levels. (728 aa)
acy-3Adenylyl CYclase. (1243 aa)
C46A5.4Uncharacterized protein. (1537 aa)
acy-1Adenylyl CYclase. (1253 aa)
pxn-2PeroXidasiN (Drosophila peroxidase) homolog. (1328 aa)
pde-2Probable 3',5'-cyclic phosphodiesterase pde-2; May negatively regulate the activity of cGMP-dependent protein kinase egl-4 which in turn controls body size. (831 aa)
pde-1Probable 3',5'-cyclic phosphodiesterase pde-1; Redundantly with pde-5, plays a role in the AFD thermosensory neurons to regulate microvilli receptive ending morphology, possibly by regulating cGMP levels. (664 aa)
T06D8.10Uncharacterized protein. (1490 aa)
pxn-1Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. (1285 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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