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gpx-8 gpx-8 gpx-4 gpx-4 sbp-1 sbp-1 pola-1 pola-1 Y37B11A.2 Y37B11A.2 fat-5 fat-5 fat-6 fat-6 gpx-6 gpx-6 mdt-15 mdt-15 gpx-2 gpx-2 gpx-7 gpx-7 cpt-4 cpt-4 nhr-49 nhr-49 acdh-8 acdh-8 gpx-5 gpx-5 gpx-3 gpx-3 art-1 art-1 ech-1.1 ech-1.1 acox-1.2 acox-1.2 fat-7 fat-7 elo-2 elo-2 gpx-1 gpx-1 acs-2 acs-2 ppt-1 ppt-1 acs-1 acs-1 acaa-2 acaa-2 lipl-4 lipl-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpx-8Glutathione PeroXidase. (145 aa)
gpx-4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (126 aa)
sbp-1BHLH domain-containing protein. (1113 aa)
pola-1DNA polymerase. (1456 aa)
Y37B11A.2DNA polymerase. (1303 aa)
fat-5Delta(9)-fatty-acid desaturase fat-5; Delta(9)-fatty-acid desaturase that acts preferentially on palmitoyl-CoA. Also acts on pentadecanoyl-coA and myristoyl-CoA. (333 aa)
fat-6Delta(9)-fatty-acid desaturase fat-6; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. Belongs to the fatty acid desaturase type 1 family. (339 aa)
gpx-6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (188 aa)
mdt-15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Require [...] (780 aa)
gpx-2Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses. (179 aa)
gpx-7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (197 aa)
cpt-4Carn_acyltransf domain-containing protein. (748 aa)
nhr-49Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. (501 aa)
acdh-8Acyl CoA DeHydrogenase. (412 aa)
gpx-5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (223 aa)
gpx-3Glutathione peroxidase 3; Belongs to the glutathione peroxidase family. (224 aa)
art-1Probable very-long-chain enoyl-CoA reductase art-1; Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precurso [...] (308 aa)
ech-1.1Enoyl-CoA Hydratase. (755 aa)
acox-1.2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
fat-7Delta(9)-fatty-acid desaturase fat-7; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA, heptadecanyol-CoA, and palmitoyl-CoA. (338 aa)
elo-2Elongation of very long chain fatty acids protein. (274 aa)
gpx-1Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses. (163 aa)
acs-2Fatty Acid CoA Synthetase family. (618 aa)
ppt-1Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides. (298 aa)
acs-1Fatty Acid CoA Synthetase family. (623 aa)
acaa-2ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
lipl-4Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (411 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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