STRINGSTRING
kin-1 kin-1 ain-1 ain-1 ccr-4 ccr-4 act-5 act-5 pir-1 pir-1 alg-5 alg-5 alg-2 alg-2 kin-2 kin-2 cog-1 cog-1 unc-119 unc-119 alg-1 alg-1 acy-1 acy-1 unc-54 unc-54 acy-3 acy-3 acy-2 acy-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kin-1cAMP-dependent protein kinase catalytic subunit; Essential for larval development. Controls the rhythmic contraction of enteric muscles probably by regulating G- protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons. Plays a role in the control of oocyte meiotic maturation by gonadal sheath cells. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (579 aa)
ain-1ALG-1 INteracting protein. (641 aa)
ccr-4Endo/exonuclease/phosphatase domain-containing protein. (677 aa)
act-5ACTin. (375 aa)
pir-1RNA/RNP complex-1-interacting phosphatase homolog; Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity (By similarity). Binds RNA (By similarity). During small-RNA-mediated gene- silencing or RNA interference (RNAi), involved in the dcr-1-mediated processing of an amplified dsRNA intermediate. (233 aa)
alg-5Protein argonaute; Belongs to the argonaute family. (905 aa)
alg-2Protein argonaute; Belongs to the argonaute family. (910 aa)
kin-2cAMP-dependent protein kinase regulatory subunit; Controls the rhythmic contraction of enteric muscles probably by regulating G-protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons; Belongs to the cAMP-dependent kinase regulatory chain family. (376 aa)
cog-1Homeobox domain-containing protein. (256 aa)
unc-119Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system. (244 aa)
alg-1Protein argonaute; Belongs to the argonaute family. (1023 aa)
acy-1Adenylyl CYclase. (1253 aa)
unc-54Myosin-4; Required for muscle contraction. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1963 aa)
acy-3Adenylyl CYclase. (1243 aa)
acy-2Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1080 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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