STRINGSTRING
clp-8 clp-8 nlp-20 nlp-20 col-103 col-103 nlp-12 nlp-12 lips-17 lips-17 daf-16 daf-16 flp-26 flp-26 clp-2 clp-2 clp-9 clp-9 T14A8.2 T14A8.2 nlp-33 nlp-33 T24C4.2 T24C4.2 asm-3 asm-3 gba-4 gba-4 Y56A3A.28 Y56A3A.28 clp-6 clp-6 clp-7 clp-7 asm-2 asm-2 nlp-28 nlp-28 nlp-29 nlp-29 nlp-30 nlp-30 sod-3 sod-3 hyl-1 hyl-1 flp-24 flp-24 nlp-39 nlp-39 pmp-3 pmp-3 sqt-3 sqt-3 flp-8 flp-8 nlp-24 nlp-24 nlp-10 nlp-10 hsp-12.6 hsp-12.6 flp-22 flp-22 pqm-1 pqm-1 nlp-17 nlp-17 tbx-43 tbx-43 clp-3 clp-3 ctl-1 ctl-1 clp-10 clp-10 clp-4 clp-4 nlp-25 nlp-25 nlp-26 nlp-26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
clp-8Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (646 aa)
nlp-20Neuropeptide-Like Protein. (99 aa)
col-103Col_cuticle_N domain-containing protein. (371 aa)
nlp-12Neuropeptide-Like Protein. (80 aa)
lips-17LIPaSe related. (280 aa)
daf-16Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] (541 aa)
flp-26FMRFamide-like neuropeptides 26; FMRFamides and FMRFamide-like peptides are neuropeptides. (84 aa)
clp-2Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (805 aa)
clp-9Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (718 aa)
T14A8.2Uncharacterized protein. (202 aa)
nlp-33Neuropeptide-like protein 33; May have antifungic activity against D.coniospora; Belongs to the YARP (YGGW-amide related peptide) family. (74 aa)
T24C4.2Uncharacterized protein. (423 aa)
asm-3Putative sphingomyelin phosphodiesterase asm-3; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (589 aa)
gba-4Putative glucosylceramidase 4; Belongs to the glycosyl hydrolase 30 family. (519 aa)
Y56A3A.28C2H2-type domain-containing protein. (386 aa)
clp-6Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (627 aa)
clp-7Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (778 aa)
asm-2Sphingomyelin phosphodiesterase 2; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (618 aa)
nlp-28Neuropeptide-like protein 28; May have antimicrobial activity; Belongs to the YARP (YGGW-amide related peptide) family. (65 aa)
nlp-29Neuropeptide-like protein 29; Antimicrobial peptides that have antibacterial activity against the Gram-negative bacteria S.marcescens. Has antifungal activity against D.coniospora. May play a role in response to physical injury and osmotic stress ; Belongs to the YARP (YGGW-amide related peptide) family. (73 aa)
nlp-30Neuropeptide-like protein 30; May have antimicrobial activity. May play a role in response to fungal infection; Belongs to the YARP (YGGW-amide related peptide) family. (69 aa)
sod-3Superoxide dismutase [Mn] 2, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (218 aa)
hyl-1Ceramide synthase hyl-1; Catalyzes the acylation of sphingosine to form ceramides. Exhibits substrate preference for fatty acyl-coA chains containing 24 and 26 carbons. (372 aa)
flp-24FMRFamide-like neuropeptides 24; FMRFamides and FMRFamide-like peptides are neuropeptides. (69 aa)
nlp-39Neuropeptide-Like Protein. (79 aa)
pmp-3Peroxisomal Membrane Protein related. (688 aa)
sqt-3Cuticle collagen 1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. (301 aa)
flp-8FMRFamide-like peptide 8. (135 aa)
nlp-24Neuropeptide-Like Protein. (80 aa)
nlp-10Neuropeptide-Like Protein. (131 aa)
hsp-12.6SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (110 aa)
flp-22FMRFamide-like neuropeptides 22; FMRFamides and FMRFamide-like peptides are neuropeptides. Belongs to the FARP (FMRFamide related peptide) family. (93 aa)
pqm-1C2H2-type domain-containing protein. (295 aa)
nlp-17Neuropeptide-Like Protein. (83 aa)
tbx-43T BoX family. (305 aa)
clp-3Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (752 aa)
ctl-1Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. (497 aa)
clp-10Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (634 aa)
clp-4Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (716 aa)
nlp-25Neuropeptide-Like Protein. (87 aa)
nlp-26Neuropeptide-Like Protein. (90 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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