36 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	acdh-13	Acyl CoA DeHydrogenase. (617 aa)
	acdh-2	Acyl CoA DeHydrogenase. (386 aa)
	pdp-1	PPM-type phosphatase domain-containing protein. (451 aa)
	pyk-2	Pyruvate kinase; Belongs to the pyruvate kinase family. (515 aa)
	cya-1	G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. (485 aa)
	aco-1	Probable cytoplasmic aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (887 aa)
	pfk-1.1	ATP-dependent 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (814 aa)
	sbp-1	BHLH domain-containing protein. (1113 aa)
	cpt-1	Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family. (779 aa)
	tpi-1	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (247 aa)
	acdh-7	Acyl CoA DeHydrogenase. (412 aa)
	acdh-4	Acyl CoA DeHydrogenase. (385 aa)
	gpd-1	Glyceraldehyde-3-phosphate dehydrogenase 1. (341 aa)
	acdh-10	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family. (417 aa)
	hsr-9	Protein hsr-9; May have a role in DNA double-strand break repair following gamma-irradiation. (1165 aa)
	pgk-1	Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
	lin-12	Protein lin-12; Involved in several cell fate decisions that require cell- cell interactions. It is possible that lin-12 encodes a membrane-bound receptor for a signal that enables expression of the ventral uterine precursor cell fate. Activity in cell fate decisions and tumorigenesis is negatively regulated by sel-10. Functions in uterine cells to promote basement membrane mobility during tissue remodeling. (1429 aa)
	asns-2	Glutamine amidotransferase type-2 domain-containing protein. (567 aa)
	gpd-2	Glyceraldehyde-3-phosphate dehydrogenase 2. (341 aa)
	gpd-3	Glyceraldehyde-3-phosphate dehydrogenase 3. (341 aa)
	acdh-3	Acyl CoA DeHydrogenase. (419 aa)
	acdh-8	Acyl CoA DeHydrogenase. (412 aa)
	cya-2	CYCLIN domain-containing protein; Belongs to the cyclin family. (123 aa)
	aco-2	Probable aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (777 aa)
	klf-2	Kruppel-Like Factor (Zinc finger protein). (299 aa)
	gpd-4	Glyceraldehyde-3-phosphate dehydrogenase 4. (341 aa)
	acdh-9	Acyl CoA DeHydrogenase. (409 aa)
	pyk-1	Pyruvate kinase; Belongs to the pyruvate kinase family. (913 aa)
	asns-1	Glutamine amidotransferase type-2 domain-containing protein. (551 aa)
	mdh-2	Probable malate dehydrogenase, mitochondrial. (341 aa)
	hxk-1	Phosphotransferase; Belongs to the hexokinase family. (500 aa)
	ldh-1	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. LDH family. (336 aa)
	acdh-12	Acyl CoA DeHydrogenase. (613 aa)
	parp-2	Poly [ADP-ribose] polymerase 2; Poly[ADP-ribose] polymerase modifies various nuclear proteins by poly(ADP-ribosyl)ation, a post-translational modification synthesized after DNA damage that appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks and programmed cell death. (538 aa)
	acdh-1	Acyl CoA DeHydrogenase. (427 aa)
	acdh-5	Acyl CoA DeHydrogenase. (442 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acdh-1	acdh-3	C55B7.4a.1	K06A5.6.2	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.902
acdh-1	acdh-4	C55B7.4a.1	T10E9.9b.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.901
acdh-1	cpt-1	C55B7.4a.1	Y46G5A.17.1	Acyl CoA DeHydrogenase.	Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family.	0.513
acdh-1	sbp-1	C55B7.4a.1	Y47D3B.7.1	Acyl CoA DeHydrogenase.	BHLH domain-containing protein.	0.401
acdh-10	acdh-12	T08G2.3.2	E04F6.5a.2	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl CoA DeHydrogenase.	0.458
acdh-10	acdh-7	T08G2.3.2	T25G12.5.1	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl CoA DeHydrogenase.	0.958
acdh-10	acdh-8	T08G2.3.2	K05F1.3.1	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl CoA DeHydrogenase.	0.901
acdh-12	acdh-10	E04F6.5a.2	T08G2.3.2	Acyl CoA DeHydrogenase.	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	0.458
acdh-12	acdh-7	E04F6.5a.2	T25G12.5.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.443
acdh-12	cpt-1	E04F6.5a.2	Y46G5A.17.1	Acyl CoA DeHydrogenase.	Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family.	0.509
acdh-13	acdh-7	C28C12.9.2	T25G12.5.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.437
acdh-13	cpt-1	C28C12.9.2	Y46G5A.17.1	Acyl CoA DeHydrogenase.	Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family.	0.414
acdh-3	acdh-1	K06A5.6.2	C55B7.4a.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.902
acdh-3	acdh-4	K06A5.6.2	T10E9.9b.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.902
acdh-4	acdh-1	T10E9.9b.1	C55B7.4a.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.901
acdh-4	acdh-3	T10E9.9b.1	K06A5.6.2	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.902
acdh-4	acdh-8	T10E9.9b.1	K05F1.3.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.423
acdh-5	acdh-8	C37A2.3.1	K05F1.3.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.703
acdh-7	acdh-10	T25G12.5.1	T08G2.3.2	Acyl CoA DeHydrogenase.	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	0.958
acdh-7	acdh-12	T25G12.5.1	E04F6.5a.2	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.443