node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atf-5 | atf-6 | T04C10.4.1 | F45E6.2.1 | BZIP domain-containing protein. | BZIP domain-containing protein. | 0.954 |
atf-5 | eif-2alpha | T04C10.4.1 | Y37E3.10a.1 | BZIP domain-containing protein. | S1 motif domain-containing protein. | 0.989 |
atf-5 | hsp-3 | T04C10.4.1 | C15H9.6a.5 | BZIP domain-containing protein. | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | 0.449 |
atf-5 | hsp-4 | T04C10.4.1 | F43E2.8a.2 | BZIP domain-containing protein. | Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. | 0.591 |
atf-5 | pek-1 | T04C10.4.1 | F46C3.1.1 | BZIP domain-containing protein. | Eukaryotic translation initiation factor 2-alpha kinase pek-1; Phosphorylates the alpha subunit of eukaryotic translation- initiation factor 2 (eIF2alpha), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. May phosphorylate eIF2alpha during hypoxia. Proposed to have a role in alleviating endoplasmic reticulum stress ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. | 0.987 |
atf-5 | xbp-1 | T04C10.4.1 | R74.3a.1 | BZIP domain-containing protein. | BZIP domain-containing protein. | 0.971 |
atf-6 | atf-5 | F45E6.2.1 | T04C10.4.1 | BZIP domain-containing protein. | BZIP domain-containing protein. | 0.954 |
atf-6 | eif-2alpha | F45E6.2.1 | Y37E3.10a.1 | BZIP domain-containing protein. | S1 motif domain-containing protein. | 0.885 |
atf-6 | hsp-3 | F45E6.2.1 | C15H9.6a.5 | BZIP domain-containing protein. | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | 0.755 |
atf-6 | hsp-4 | F45E6.2.1 | F43E2.8a.2 | BZIP domain-containing protein. | Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. | 0.837 |
atf-6 | pek-1 | F45E6.2.1 | F46C3.1.1 | BZIP domain-containing protein. | Eukaryotic translation initiation factor 2-alpha kinase pek-1; Phosphorylates the alpha subunit of eukaryotic translation- initiation factor 2 (eIF2alpha), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. May phosphorylate eIF2alpha during hypoxia. Proposed to have a role in alleviating endoplasmic reticulum stress ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. | 0.978 |
atf-6 | xbp-1 | F45E6.2.1 | R74.3a.1 | BZIP domain-containing protein. | BZIP domain-containing protein. | 0.995 |
eif-2alpha | atf-5 | Y37E3.10a.1 | T04C10.4.1 | S1 motif domain-containing protein. | BZIP domain-containing protein. | 0.989 |
eif-2alpha | atf-6 | Y37E3.10a.1 | F45E6.2.1 | S1 motif domain-containing protein. | BZIP domain-containing protein. | 0.885 |
eif-2alpha | hsp-3 | Y37E3.10a.1 | C15H9.6a.5 | S1 motif domain-containing protein. | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | 0.548 |
eif-2alpha | hsp-4 | Y37E3.10a.1 | F43E2.8a.2 | S1 motif domain-containing protein. | Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. | 0.633 |
eif-2alpha | pek-1 | Y37E3.10a.1 | F46C3.1.1 | S1 motif domain-containing protein. | Eukaryotic translation initiation factor 2-alpha kinase pek-1; Phosphorylates the alpha subunit of eukaryotic translation- initiation factor 2 (eIF2alpha), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. May phosphorylate eIF2alpha during hypoxia. Proposed to have a role in alleviating endoplasmic reticulum stress ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. | 0.999 |
eif-2alpha | xbp-1 | Y37E3.10a.1 | R74.3a.1 | S1 motif domain-containing protein. | BZIP domain-containing protein. | 0.908 |
hsp-3 | atf-5 | C15H9.6a.5 | T04C10.4.1 | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | BZIP domain-containing protein. | 0.449 |
hsp-3 | atf-6 | C15H9.6a.5 | F45E6.2.1 | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | BZIP domain-containing protein. | 0.755 |