Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZK970.8 | act-5 | ZK970.8.1 | T25C8.2.2 | Uncharacterized protein. | ACTin. | 0.912 |
| ZK970.8 | cdc-42 | ZK970.8.1 | R07G3.1.1 | Uncharacterized protein. | Cell division control protein 42 homolog; Plays an essential role in spindle orientation and organizing cellular and embryonic polarity by controlling the localization and activity of PAR (partitioning-defective) proteins. Required for maintaining the asymmetric cortical localization of the anterior complex proteins par-3 and par-6, the posterior cortical protein par-2, and pkc-3. Involved in hypodermal cell fusion, together with pak-1 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. During gonad morphogenesis, plays a role in dista [...] | 0.927 |
| ZK970.8 | ced-10 | ZK970.8.1 | C09G12.8b.1 | Uncharacterized protein. | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | 0.848 |
| ZK970.8 | cgef-1 | ZK970.8.1 | C14A11.3b.1 | Uncharacterized protein. | DH domain-containing protein. | 0.438 |
| ZK970.8 | mig-1 | ZK970.8.1 | Y34D9B.1b.1 | Uncharacterized protein. | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.540 |
| ZK970.8 | mig-2 | ZK970.8.1 | C35C5.4a.1 | Uncharacterized protein. | Rac-like GTPase. | 0.572 |
| ZK970.8 | pkc-3 | ZK970.8.1 | F09E5.1.1 | Uncharacterized protein. | Protein kinase C-like 3; Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury. | 0.594 |
| ZK970.8 | rho-1 | ZK970.8.1 | Y51H4A.3a.1 | Uncharacterized protein. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.943 |
| ZK970.8 | zen-4 | ZK970.8.1 | M03D4.1d.2 | Uncharacterized protein. | Kinesin-like protein. | 0.491 |
| act-5 | ZK970.8 | T25C8.2.2 | ZK970.8.1 | ACTin. | Uncharacterized protein. | 0.912 |
| act-5 | anc-1 | T25C8.2.2 | ZK973.6a.1 | ACTin. | Nuclear anchorage protein 1; Plays a central role in nuclear and mitochondrial anchoring. Probably connects nuclei to the cytoskeleton by interacting with unc-84 at the nuclear envelope and with F-actin in the cytoplasm, creating a bridge across the nuclear envelope between the cytoskeleton and the nucleus. Has a role in positioning of the cell body of the PVQ lumbar interneuron. Belongs to the nesprin family. | 0.865 |
| act-5 | arx-3 | T25C8.2.2 | Y79H2A.6b.1 | ACTin. | Actin-related protein 2/3 complex subunit. | 0.832 |
| act-5 | cdc-42 | T25C8.2.2 | R07G3.1.1 | ACTin. | Cell division control protein 42 homolog; Plays an essential role in spindle orientation and organizing cellular and embryonic polarity by controlling the localization and activity of PAR (partitioning-defective) proteins. Required for maintaining the asymmetric cortical localization of the anterior complex proteins par-3 and par-6, the posterior cortical protein par-2, and pkc-3. Involved in hypodermal cell fusion, together with pak-1 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. During gonad morphogenesis, plays a role in dista [...] | 0.976 |
| act-5 | ced-10 | T25C8.2.2 | C09G12.8b.1 | ACTin. | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | 0.879 |
| act-5 | ced-3 | T25C8.2.2 | C48D1.2a.1 | ACTin. | Cell death protein 3 subunit p13; Acts as a cysteine protease in controlling programmed cell death (apoptosis) by proteolytically activating or inactivating a wide range of substrates. Component of the egl-1, ced-9, ced-4 and ced-3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During oogenesis, required for germline apoptosis downstream of ced-9 and ced-4 but independently of egl-1. By cleaving and activating ced-8, promotes phosphatidylserine exposure on the surface of apoptotic ce [...] | 0.726 |
| act-5 | dpy-10 | T25C8.2.2 | T14B4.7.1 | ACTin. | Cuticle collagen dpy-10; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. | 0.417 |
| act-5 | mig-1 | T25C8.2.2 | Y34D9B.1b.1 | ACTin. | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.699 |
| act-5 | mig-2 | T25C8.2.2 | C35C5.4a.1 | ACTin. | Rac-like GTPase. | 0.752 |
| act-5 | nmy-2 | T25C8.2.2 | F20G4.3.1 | ACTin. | Non-muscle MYosin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.961 |
| act-5 | par-6 | T25C8.2.2 | T26E3.3a.1 | ACTin. | Partitioning defective protein 6; Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Regulates mes-1 expression and/or localization pattern during early embryogenesis. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. Plays a role in endosome and Golgi body positioning. Belongs to the PAR6 family. | 0.660 |
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