node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hda-10 | hda-11 | Y51H1A.5.1 | C35A5.9.1 | Hist_deacetyl domain-containing protein. | Hist_deacetyl domain-containing protein. | 0.621 |
hda-10 | hda-3 | Y51H1A.5.1 | R06C1.1.1 | Hist_deacetyl domain-containing protein. | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.749 |
hda-11 | hda-10 | C35A5.9.1 | Y51H1A.5.1 | Hist_deacetyl domain-containing protein. | Hist_deacetyl domain-containing protein. | 0.621 |
hda-11 | hda-3 | C35A5.9.1 | R06C1.1.1 | Hist_deacetyl domain-containing protein. | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.519 |
hda-11 | hda-5 | C35A5.9.1 | F43G6.11.1 | Hist_deacetyl domain-containing protein. | Hist_deacetyl domain-containing protein. | 0.542 |
hda-3 | hda-10 | R06C1.1.1 | Y51H1A.5.1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | Hist_deacetyl domain-containing protein. | 0.749 |
hda-3 | hda-11 | R06C1.1.1 | C35A5.9.1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | Hist_deacetyl domain-containing protein. | 0.519 |
hda-3 | hda-5 | R06C1.1.1 | F43G6.11.1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | Hist_deacetyl domain-containing protein. | 0.633 |
hda-3 | smo-1 | R06C1.1.1 | K12C11.2.1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.538 |
hda-3 | ubc-9 | R06C1.1.1 | F29B9.6.2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.517 |
hda-5 | hda-11 | F43G6.11.1 | C35A5.9.1 | Hist_deacetyl domain-containing protein. | Hist_deacetyl domain-containing protein. | 0.542 |
hda-5 | hda-3 | F43G6.11.1 | R06C1.1.1 | Hist_deacetyl domain-containing protein. | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.633 |
smo-1 | hda-3 | K12C11.2.1 | R06C1.1.1 | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.538 |
smo-1 | ubc-9 | K12C11.2.1 | F29B9.6.2 | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.999 |
ubc-9 | hda-3 | F29B9.6.2 | R06C1.1.1 | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.517 |
ubc-9 | smo-1 | F29B9.6.2 | K12C11.2.1 | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.999 |