STRINGSTRING
C01G6.5 C01G6.5 Y53G8AL.1 Y53G8AL.1 chk-2 chk-2 ZK632.2 ZK632.2 M4.1 M4.1 mcrs-1 mcrs-1 klp-4 klp-4 unc-104 unc-104 athp-1 athp-1 C32E8.5 C32E8.5 nbs-1 nbs-1 T08D2.7 T08D2.7 B0511.7 B0511.7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C01G6.5Uncharacterized protein C01G6.5. (952 aa)
Y53G8AL.1FHA domain-containing protein. (1115 aa)
chk-2Serine/threonine-protein kinase chk-2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase. (476 aa)
ZK632.2Uncharacterized protein ZK632.2. (710 aa)
M4.1FHA domain-containing protein. (578 aa)
mcrs-1FHA domain-containing protein. (478 aa)
klp-4Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1610 aa)
unc-104Kinesin-like protein unc-104; Motor protein involved in microtubule-associated anterograde transport. Regulates the transport of synaptic vesicle precursors in the axon of DA motor neurons. Regulates the polarized sorting of axonal proteins. Essential for the transport of synaptic components during the synaptic remodeling of the DD motor neuron, probably downstream of cdk-5 and/or pct-1/cyy-1 complex. Required for the anterograde transport of neuropeptide-containing dense core vesicles along axons. Involved in necrotic cell death. Belongs to the TRAFAC class myosin-kinesin ATPase super [...] (1628 aa)
athp-1AT Hook plus PHD finger transcription factor. (1150 aa)
C32E8.5FHA domain-containing protein. (299 aa)
nbs-1FHA domain-containing protein. (362 aa)
T08D2.7Uncharacterized protein; Belongs to the protein kinase superfamily. (469 aa)
B0511.7FHA domain-containing protein. (302 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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