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| | scp-1 | SREBP Cleavage activating Protein (SCAP) homolog. (1087 aa) |
| | lin-53 | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] (417 aa) |
| | rba-1 | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. (412 aa) |
| | nmtn-1 | WD_REPEATS_REGION domain-containing protein. (942 aa) |
| | atg-16.2 | Autophagic-related protein 16.2; Most likely a component of the atg-5-atg-12-atg-16.1/atg-16.2 complex, which is recruited to the preautophagosomal membrane and associates with lgg-2 to promote autophagosome formation. Plays a role in the recruitment of lipidated lgg-1 probably to the autophagosome membrane to promote autophagosome formation. Furthermore, association with atg-5 is required for the nucleation of lgg-1 positive autophagosomes. Although its role in autophagosome formation may be distinct to the role of atg-16.2, it functions in a partially redundant manner with atg-16.1 t [...] (534 aa) |
| | wdr-5.2 | WD repeat-containing protein wdr-5.2; Sex determining protein required in the germline to promote the spermatogenesis to oogenesis switch during the late larval stages of development. Acts with the sex determining factor tra-1, and redundantly with wdr-5.1, to regulate fog-3 expression, which in turn determines germ cell fate. Not required for methylation of histone H3 'Lys-4'. (395 aa) |
| | rack-1 | Guanine nucleotide-binding protein subunit beta-2-like 1; Required for the expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury. (325 aa) |
| | sec-12 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | JC8.2 | WD_REPEATS_REGION domain-containing protein. (467 aa) |
| | H24G06.1 | Uncharacterized protein. (1657 aa) |
| | wdr-12 | Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (439 aa) |
| | F55F8.3 | Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family. (910 aa) |
| | sel-10 | F-box/WD repeat-containing protein sel-10; Probable substrate recognition component of SCF (SKP1-CUL-F- box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates synapse elimination in early development in the motor neuron HSNL. Cell autonomous negative regulator of lin-12/Notch-mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis. May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation. Involved in sex determin [...] (587 aa) |
| | rbc-1 | WD_REPEATS_REGION domain-containing protein. (3027 aa) |
| | swan-1 | WD_REPEATS_REGION domain-containing protein. (388 aa) |
| | swan-2 | WD_REPEATS_REGION domain-containing protein. (478 aa) |
| | sorf-2 | Suppressor of organelle fusion 2; Together with sorf-1 negatively regulates the levels of phosphatidylinositol 3-phosphate (PtdIns3P) to enable the conversion of early endosomes to late endosomes. Binds to sorf-1 and the sorf-1-sorf- 2 complex likely acts through bec-1, a non-catalytic subunit of phosphatidylinositol 3-kinase (PI3K), to suppress PI3K activity, thereby negatively regulating endosomal PtdIns3P levels. Belongs to the WD repeat WDR81 family. (1422 aa) |
| | gpb-2 | Guanine nucleotide-binding protein subunit beta-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (369 aa) |
| | F49D11.10 | Uncharacterized protein. (727 aa) |
| | prp-17 | WD_REPEATS_REGION domain-containing protein. (567 aa) |
| | F47G4.4 | Uncharacterized protein. (722 aa) |
| | F47D12.9 | Uncharacterized WD repeat-containing protein F47D12.9. (545 aa) |
| | F46C5.9 | WD_REPEATS_REGION domain-containing protein. (451 aa) |
| | atg-18 | Autophagy-related protein 18; Component of the autophagy machinery that is recruited to phosphatidylinositols on preautophagosomal structures, which are early autophagic structures, to promote autophagosome formation, and the subsequent degradation and clearance of engulfed apoptotic cells and P- granules in somatic cells. In particular, binds with high affinity to phosphatidylinositols including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), and more weakly to phosphatidylinositol 3,5-bis [...] (412 aa) |
| | F39H12.2 | WD_REPEATS_REGION domain-containing protein. (347 aa) |
| | che-2 | CHE-2 protein. (760 aa) |
| | copb-2 | Probable coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity); Belongs to the WD repeat COPB2 family. (1000 aa) |
| | elp-1 | Echinoderm microtubule-associated protein-like elp-1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; Belongs to the WD repeat EMAP family. (891 aa) |
| | wdr-48 | WD repeat-containing protein 48 homolog; Together with wdr-20, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor. (697 aa) |
| | F33G12.2 | WD_REPEATS_REGION domain-containing protein. (305 aa) |
| | thoc-3 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | nol-10 | NUC153 domain-containing protein. (754 aa) |
| | panl-2 | Uncharacterized protein F31E3.4. (1131 aa) |
| | taf-5 | TAF (TBP-associated transcription factor) family. (648 aa) |
| | wdr-46 | WD_REPEATS_REGION domain-containing protein. (580 aa) |
| | cpf-1 | WD_REPEATS_REGION domain-containing protein. (430 aa) |
| | sur-6 | Serine/threonine-protein phosphatase 2A regulatory subunit sur-6; Probable regulatory subunit of serine/threonine phosphatase let-92. Together with let-92 and constant regulatory subunit paa-1, positively regulates centriole duplication during early embryonic cell divisions by preventing the degradation of sas-5 and kinase zyg-1. In addition, during vulva development, may play a role with phosphatase let-92 and regulatory subunit paa-1 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase signaling, probably by promoting lin-45 activation. In intesti [...] (495 aa) |
| | daf-10 | Intraflagellar transport protein 122 homolog; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs). Plays a role in chemotaxis and sensory perception. Required for entry into and exit from the dauer larval stage and this may be mediated by daf-12, daf-16 and daf-41. Controls the behavioral response, namely the avoidance response, and pathogen-responsive gene expression in the response to pathogenic bacteria such as E.coli and P. aeruginosa. (1192 aa) |
| | rbbp-5 | Retinoblastoma-binding protein homolog 5; Required for di- and trimethylation at 'Lys-4' of histone H3. (454 aa) |
| | ctf-4 | Mcl1_mid domain-containing protein. (1101 aa) |
| | F13H8.2 | WD_REPEATS_REGION domain-containing protein. (929 aa) |
| | gpb-1 | Guanine nucleotide-binding protein subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces. (340 aa) |
| | rae-1 | mRNA export factor rae-1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). It is specifically important for nuclear mRNA export. Has a role in neuronal development, where it acts downstream of rpm-1 to control axon termination and synapse formation in anterior lateral microtubule (ALM) and posterior lateral microtubule (PLM) mechanosensory neurons. Belo [...] (373 aa) |
| | sel-2 | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. (2507 aa) |
| | snrp-40.1 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | F02E9.10 | WD_REPEATS_REGION domain-containing protein. (455 aa) |
| | atg-16.1 | Autophagic-related protein 16.1; Most likely a component of the atg-5-atg-12-atg-16.1/atg-16.2 complex, which is recruited to the preautophagosomal membrane and associates with lgg-2 to promote autophagosome formation. Although its role in autophagosome formation may be distinct to the role of atg-16.2, it functions in a partially redundant manner with atg-16.2 to regulate autophagic processes. (578 aa) |
| | wdr-23 | DDB1- and CUL4-associated factor 11 homolog; Involved in regulation of lifespan. Required for dopaminergic CEP neuron degeneration in response to Mn(2+). (571 aa) |
| | fzr-1 | WD_REPEATS_REGION domain-containing protein. (702 aa) |
| | fzy-1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. (507 aa) |
| | ZK430.7 | WD_REPEATS_REGION domain-containing protein. (444 aa) |
| | dyf-2 | WD repeat-containing protein dyf-2; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Moves along the ciliary axoneme and is involved in the assembly, localization and the movement of other intraflagellar transport (IFT) proteins along the cilia axoneme. May also associate with the BBSome complex in order to mediate ciliary transport. Regulates cilia biogenesis, morphology and sensitivity to environmental cues. (1383 aa) |
| | vps-15 | Related to yeast Vacuolar Protein Sorting factor. (1354 aa) |
| | B0280.9 | U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. (429 aa) |
| | unc-78 | Actin-interacting protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Regulator of actin organization in myofibrils. (611 aa) |
| | ufd-3 | Ubiquitin fusion degradation protein 3 homolog; Plays a role in protein ubiquitination, sorting and degradation through its association with cdc-48.1 and/or cdc-48.2. (860 aa) |
| | C05D2.10 | WD_REPEATS_REGION domain-containing protein. (486 aa) |
| | wdr-20 | WD repeat-containing protein 20 homolog; Together with wdr-48, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor. (768 aa) |
| | mes-6 | Polycomb protein mes-6; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes- 6 complex may participate in the global inactivation of the X chromosomes in germline cells. The complex may act via methylation of histone H3 'Lys-27', rendering chromatin heritably changed in its expressibility. This complex is required to ex [...] (459 aa) |
| | npp-23 | Nuclear Pore complex Protein. (371 aa) |
| | C10B5.1 | WD_REPEATS_REGION domain-containing protein. (311 aa) |
| | daf-15 | Raptor_N domain-containing protein. (1800 aa) |
| | mlst-8 | WD_REPEATS_REGION domain-containing protein. (382 aa) |
| | wdr-5.1 | WD repeat-containing protein wdr-5.1; Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. Required for di- and trimethylation, particularly for the trimethylation at 'Lys-4' of histone H3. Not required for demethylation of histone H3 'Lys-27'. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, germline establishment, maintenance and function. Implicated in the epigenetic inheritance of lifespan over several generations. Acts in the germline to limit the longevity of the soma, pr [...] (376 aa) |
| | dyci-1 | WD_REPEATS_REGION domain-containing protein. (643 aa) |
| | snrp-40.2 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | wdfy-3 | WD40 and FYVE domain protein. (3358 aa) |
| | che-11 | Uncharacterized protein. (1437 aa) |
| | C27F2.1 | WD Repeat protein. (673 aa) |
| | swd-2.1 | WD_REPEATS_REGION domain-containing protein. (322 aa) |
| | swd-2.2 | WD_REPEATS_REGION domain-containing protein. (326 aa) |
| | prp-4 | WD_REPEATS_REGION domain-containing protein. (496 aa) |
| | ifta-1 | WD_REPEATS_REGION domain-containing protein. (1246 aa) |
| | smu-1 | Smu-1 suppressor of mec-8 and unc-52 protein; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Selectively regulates alternative splicing of unc-52 exon 17. Thus, smu-1 mutants selectively suppress the effects of unc-52 nonsense mutations in exon 17 by promoting the accumulation of unc-52 isoforms that lack exon 17 and enhance the effects of unc-52 mutations that affect the exon 16 splice donor site. In contrast, smu-1 mutants do not suppress unc-52 nonsense mutations in exon 18. (510 aa) |
| | plrg-1 | WD_REPEATS_REGION domain-containing protein. (494 aa) |
| | wdfy-2 | WD repeat and FYVE domain-containing protein 2; Plays a role in coelomocyte endocytosis. (415 aa) |
| | csa-1 | Cockayne Syndrome complementation group A homolog. (360 aa) |
| | wdr-5.3 | WD repeat-containing protein wdr-5.3; Not required for methylation of histone H3 'Lys-4'. Belongs to the WD repeat WDR5/wds family. (501 aa) |
| | cyn-15 | PPIase cyclophilin-type domain-containing protein. (629 aa) |
| | eipr-1 | EARP-interacting protein 1; Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the endosome-associated recycling protein (EARP) complex. Important for neuronal function. Belongs to the WD repeat EIPR1 family. (362 aa) |
| | arx-3 | Actin-related protein 2/3 complex subunit. (375 aa) |
| | npp-20 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Belongs to the WD repeat SEC13 family. (313 aa) |
| | pod-1 | Uncharacterized protein. (1136 aa) |
| | eif-3.I | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (327 aa) |
| | adpr-1 | WD_REPEATS_REGION domain-containing protein. (558 aa) |
| | chaf-2 | WD_REPEATS_REGION domain-containing protein. (489 aa) |
| | tub-2 | WD_REPEATS_REGION domain-containing protein; Belongs to the TUB family. (869 aa) |
| | copa-1 | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1232 aa) |
| | Y54H5A.1 | WD_REPEATS_REGION domain-containing protein. (453 aa) |
| | bub-3 | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. (343 aa) |
| | Y54G2A.12 | WD_REPEATS_REGION domain-containing protein. (274 aa) |
| | rbc-2 | RaBConnectin related. (1322 aa) |
| | Y54E5B.2 | WD_REPEATS_REGION domain-containing protein. (861 aa) |
| | Y53C12B.1 | WD_REPEATS_REGION domain-containing protein. (793 aa) |
| | Y50C1A.2 | Uncharacterized protein. (406 aa) |
| | Y48B6A.1 | Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (674 aa) |
| | Y45F10D.7 | Uncharacterized protein. (924 aa) |
| | qui-1 | WD_REPEATS_REGION domain-containing protein. (1592 aa) |
| | Y44F5A.1 | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (383 aa) |
| | Y43F4B.9 | WD_REPEATS_REGION domain-containing protein. (309 aa) |
| | npp-18 | Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus. (363 aa) |
| | Y41C4A.32 | WD_REPEATS_REGION domain-containing protein. (291 aa) |
| | Y39H10A.6 | WD_REPEATS_REGION domain-containing protein. (672 aa) |
| | Y39G10AR.9 | WD_REPEATS_REGION domain-containing protein. (419 aa) |
| | epg-6 | Ectopic P granules protein 6; Component of the epg-6/atg-2 complex, which is involved in the generation of autophagosomes from omegasomes and in the distribution of atg-9 and atg-13 during the autophagy-mediated degradation of protein aggregates. Binds to phosphatidylinositols on preautophagosomes, which are early autophagic structures, to promote autophagosome formation. In particular, binds with high affinity to phosphatidylinositols including phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P), but more weakly to phosphatidylinositol 4- ph [...] (388 aa) |
| | Y32H12A.8 | WD_REPEATS_REGION domain-containing protein. (3849 aa) |
| | Y23H5B.5 | WD_REPEATS_REGION domain-containing protein. (561 aa) |
| | Y18D10A.9 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins; Belongs to the WD repeat CIA1 family. (337 aa) |
| | elpc-2 | ELongator complex Protein Component. (778 aa) |
| | Y111B2A.12 | WD_REPEATS_REGION domain-containing protein. (417 aa) |
| | Y110A7A.9 | WD_REPEATS_REGION domain-containing protein. (1019 aa) |
| | tcab-1 | Telomerase CAjal Body protein 1 homolog. (449 aa) |
| | wdr-4 | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (391 aa) |
| | W09G3.6 | Uncharacterized protein. (1125 aa) |
| | W07E6.2 | WD_REPEATS_REGION domain-containing protein. (473 aa) |
| | unc-37 | Transcription factor unc-37; Transcriptional corepressor that functions with the neural specificity gene unc-4 to govern motor neuron identity. May function with transcription factor mls-1 to promote uterine muscle specification and formation. (612 aa) |
| | osm-1 | Intraflagellar transport protein osm-1; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues. (1737 aa) |
| | T23B12.6 | BTB domain-containing protein. (670 aa) |
| | T18D3.1 | Uncharacterized protein. (523 aa) |
| | prp-19 | Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs. Belongs to the WD repeat PRP19 family. (492 aa) |
| | T06E6.1 | Uncharacterized protein. (431 aa) |
| | gad-1 | Gastrulation defective protein 1; Required for initiation of gastrulation. (620 aa) |
| | T05C3.2 | Uncharacterized protein. (1793 aa) |
| | T05A8.5 | WD_REPEATS_REGION domain-containing protein. (378 aa) |
| | lis-1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as nuclear migration during cell division. Part of a complex with nud-2, which is recruited to the nuclear envelope by unc-83, where, in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells. Plays a role in GABAergic synaptic vesicle localization in [...] (404 aa) |
| | T02H6.1 | WD_REPEATS_REGION domain-containing protein. (540 aa) |
| | sec-31 | WD_REPEATS_REGION domain-containing protein. (1083 aa) |
| | klp-12 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1605 aa) |
| | mec-15 | F-box/WD repeat-containing protein mec-15; Plays a role in mechanosensory transduction (touch sensitivity), touch receptor neuron development and synapse formation. Regulates expression of the protein snb-1 and the distribution of synaptic vesicles at synapses to promote synaptic transmission at the neuromuscular junctions of GABAergic motor neurons. (406 aa) |
| | cdt-2 | WD_REPEATS_REGION domain-containing protein. (682 aa) |
| | pro-1 | Pre-rRNA-processing protein pro-1; Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation. Required in the soma to promote normal proliferation and prevent germline tumor formation. Belongs to the WD repeat IPI3/WDR18 family. (529 aa) |
| | R11D1.1 | Uncharacterized protein. (622 aa) |
| | pfs-2 | pre-mRNA 3' end processing protein pfs-2; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing. (820 aa) |
| | sym-4 | SYM-4. (1043 aa) |
| | cor-1 | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. (607 aa) |
| | tom-1 | LLGL domain-containing protein. (1255 aa) |
| | hira-1 | Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (935 aa) |
| | lin-23 | F-box/WD repeat-containing protein lin-23; Functions cell autonomously to negatively regulate cell cycle progression. Required to restrain cell proliferation in response to developmental cues. Probably recognizes and binds to some proteins and promotes their ubiquitination and degradation (By similarity). (667 aa) |
| | aipl-1 | WD_REPEATS_REGION domain-containing protein. (600 aa) |
| | cash-1 | WD_REPEATS_REGION domain-containing protein. (678 aa) |
