STRINGSTRING
ets-4 ets-4 elf-1 elf-1 svh-5 svh-5 lin-1 lin-1 ets-5 ets-5 ets-8 ets-8 ets-10 ets-10 ets-9 ets-9 F19F10.1 F19F10.1 ets-7 ets-7 ast-1 ast-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ets-4Transcription factor ets-4; Transcription factor which binds to 5'-GGAA/T-3' DNA consensus sequences. Both positively and negatively regulates the expression of target genes. Plays a role in the regulation of adult lifespan, which may in part be through modulation of daf-16 activity. Regulates the expression of genes such as svh-2 in response to axon injury and in addition, may function downstream of the cAMP signaling pathway to promote axon regeneration. Regulates the expression of lipid metabolism genes and may also control the expression of the RNA-binding protein rege-1 which too [...] (437 aa)
elf-1ETS domain-containing protein. (420 aa)
svh-5Uncharacterized protein. (493 aa)
lin-1ETS domain-containing protein. (441 aa)
ets-5ETS domain-containing transcription factor ets-5; Transcription factor that plays a role in the differentiation and function of the CO(2)- and O(2)-sensing BAG neurons. The BAG neurons are required for the behavioral avoidance of environmental CO(2) and the sensing of decreased O(2) levels. Promotes the expression of genes that play a role in CO(2)- and O(2)-sensing and in egg-laying in the BAG neurons. Positively regulates the transcription of the receptor-type guanylate cyclase gcy-9, which is a critical component of the CO(2) transduction pathway, in the BAG neurons. May mediate tra [...] (246 aa)
ets-8ETS domain-containing protein. (141 aa)
ets-10ETS class transcription factor. (148 aa)
ets-9ETS domain-containing protein. (396 aa)
F19F10.1ETS domain-containing protein. (210 aa)
ets-7ETS domain-containing protein. (218 aa)
ast-1ETS domain-containing protein. (377 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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