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| | rbm-17 | RNA Binding Motif protein homolog. (371 aa) |
| | cel-1 | Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (623 aa) |
| | mog-4 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4; ATP-binding RNA helicase involved in pre-mRNA splicing (Probable). Operates during embryogenesis. (1008 aa) |
| | nxf-1 | Nuclear RNA export factor 1; Involved in RNA export from the nucleus to the cytoplasm; Belongs to the NXF family. (609 aa) |
| | unc-75 | RRM domain-containing protein. (514 aa) |
| | pabp-2 | RRM domain-containing protein. (205 aa) |
| | tag-72 | mRNA cap guanine-N7 methyltransferase; mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family. (380 aa) |
| | sup-46 | SUPpressor. (454 aa) |
| | fust-1 | FUS/TLS RNA binding protein homolog. (448 aa) |
| | rsp-6 | Probable splicing factor, arginine/serine-rich 6; Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaprodites. Required for the development of somatic gonad structures and for progression from larval stage to adulthood; Belongs to the splicing factor SR family. (179 aa) |
| | prp-4 | WD_REPEATS_REGION domain-containing protein. (496 aa) |
| | hrpl-1 | Heterogeneous nuclear RibonucleoProtein (HnRNP) L homolog. (597 aa) |
| | prp-8 | Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. (2329 aa) |
| | snr-4 | Probable small nuclear ribonucleoprotein Sm D2; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity). (118 aa) |
| | rsp-7 | Probable splicing factor, arginine/serine-rich 7. (452 aa) |
| | ptb-1 | Putative RNA-binding protein PTB-1a. (615 aa) |
| | madd-3 | Probable dual specificity protein kinase madd-3; [Isoform a]: Probable dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Negatively regulates p38 MAPK signaling to allow for the plasma membrane of body wall muscle cells to form projections, also called muscle arms, that extend and connect the body wall muscles to target motor neurons. Negative regulation of p38 MAPK signaling may in turn modulate the trafficking of the muscle specific receptor eva-1 to the lysosome, to ensure proper display of the eva-1 receptor on the plasma membrane of muscle [...] (890 aa) |
| | mog-5 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5; Could act late in the splicing of pre-mRNA and mediate the release of the spliced mRNA from spliceosomes; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily. (1200 aa) |
| | rsp-4 | Probable splicing factor, arginine/serine-rich 4; May play a functionally redundant role in embryogenesis. Belongs to the splicing factor SR family. (196 aa) |
| | snrp-40.1 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | cpsf-2 | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. (843 aa) |
| | repo-1 | Matrin-type domain-containing protein. (222 aa) |
| | cpsf-4 | Cleavage and Polyadenylation Specificity Factor. (302 aa) |
| | prpf-4 | Protein kinase domain-containing protein. (775 aa) |
| | him-1 | Structural maintenance of chromosomes protein 1; Involved in chromosome cohesion during cell cycle and in DNA repair (By similarity). Required for chromosome segregation during mitosis. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity). (1262 aa) |
| | F28C1.1 | DRY_EERY domain-containing protein. (672 aa) |
| | cpf-1 | WD_REPEATS_REGION domain-containing protein. (430 aa) |
| | suf-1 | Suf domain-containing protein. (735 aa) |
| | rsr-1 | PWI domain-containing protein. (601 aa) |
| | ama-1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1856 aa) |
| | ncbp-1 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-1 does not bind directly capped RNAs (m7GpppG- capped RNA) but is required to stabilize the movement of the N-terminal loop of ncbp-2 and lock the CBC into a high affinity cap-binding state with the c [...] (798 aa) |
| | F43G6.5 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (554 aa) |
| | cfim-1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa) |
| | F47G9.1 | GOLD domain-containing protein. (204 aa) |
| | prp-17 | WD_REPEATS_REGION domain-containing protein. (567 aa) |
| | cpf-2 | RRM domain-containing protein. (336 aa) |
| | ddx-15 | Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. (739 aa) |
| | hrp-2 | HnRNP A1 homolog. (611 aa) |
| | clpf-1 | Protein clpf-1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily. (428 aa) |
| | mog-2 | Probable U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Required maternally for early embryonic development and zygotically for germline and somatic development. Has a role in the switch from mitosis to meiosis. Might function in alternative splicing. (253 aa) |
| | teg-4 | CPSF_A domain-containing protein. (1220 aa) |
| | mog-1 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. (1131 aa) |
| | rnp-7 | RRM domain-containing protein. (332 aa) |
| | rnp-3 | RNP (RRM RNA binding domain) containing. (217 aa) |
| | rnp-2 | RNP (RRM RNA binding domain) containing. (206 aa) |
| | spt-5 | Transcription elongation factor SPT5; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex. Belongs to the SPT5 family. (1208 aa) |
| | dcr-1 | Death-promoting deoxyribonuclease; Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing. Belongs to the helicase family. Dicer subfamily. (1910 aa) |
| | prp-3 | Yeast PRP (Splicing factor) related. (621 aa) |
| | etr-1 | RRM domain-containing protein. (589 aa) |
| | rha-1 | ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Binds to DNA, RNA and small interfering siRNA. Plays a role in DNA replicat [...] (1301 aa) |
| | sftb-1 | SF3b1 domain-containing protein. (1322 aa) |
| | rbm-5 | RNA Binding Motif protein homolog. (925 aa) |
| | gut-2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (97 aa) |
| | T13H5.4 | Matrin-type domain-containing protein. (500 aa) |
| | bath-43 | BTB and MATH domain-containing protein 43; In complex with a cullin, may act in ubiquitination and proteasomal degradation processes. (451 aa) |
| | snr-3 | Probable small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures (By similarity). Belongs to the snRNP core protein family. (126 aa) |
| | rsp-2 | Probable splicing factor, arginine/serine-rich 2; Plays a functionally redundant role in spermatogenesis and growth rate control. Required for the development of somatic gonad structures and for progression from larval stage to adulthood. Belongs to the splicing factor SR family. (281 aa) |
| | rsp-1 | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. (312 aa) |
| | sftb-2 | PSP domain-containing protein. (602 aa) |
| | prp-21 | Yeast PRP (Splicing factor) related. (655 aa) |
| | rsp-3 | Probable splicing factor, arginine/serine-rich 3; Plays an essential role in embryogenesis. (258 aa) |
| | prmt-1 | Protein arginine N-methyltransferase 1; Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in target proteins. Catalyzes the formation of monomethylarginine and asymmetric dimethylarginine on histones H2A and H4, a specific tag for epigenetic transcriptional activation. Catalyzes asymmetric arginine dimethylation of mitochondrial proteins necessary for mitochondrial oxidative phosphorylation activity and thus aerobic respiration and ATP synthesis, and the mitochondrial stress response. Methylates arginine r [...] (348 aa) |
| | snr-1 | Small nuclear ribonucleoprotein Sm D3; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity); Belongs to the snRNP core protein family. (136 aa) |
| | teg-1 | Tumorous Enhancer of Glp-1(Gf). (353 aa) |
| | xrn-2 | 5'-3' exoribonuclease 2 homolog; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle. (975 aa) |
| | snr-6 | Probable small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (90 aa) |
| | phf-5 | PHd Finger family. (110 aa) |
| | rbm-39 | RNA Binding Motif protein homolog. (580 aa) |
| | Y55F3BR.1 | Uncharacterized protein. (728 aa) |
| | prp-6 | Yeast PRP (Splicing factor) related. (968 aa) |
| | cpsf-3 | Cleavage and Polyadenylation Specificity Factor. (707 aa) |
| | dnj-30 | J domain-containing protein. (238 aa) |
| | snr-7 | Probable small nuclear ribonucleoprotein G; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (77 aa) |
| | hrpf-2 | RRM domain-containing protein. (610 aa) |
| | cpsf-1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). (1454 aa) |
| | uaf-1 | Splicing factor U2AF 65 kDa subunit; Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity). (496 aa) |
| | eftu-2 | Tr-type G domain-containing protein. (974 aa) |
| | lsm-7 | Sm domain-containing protein. (104 aa) |
| | snr-5 | Probable small nuclear ribonucleoprotein F; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. (85 aa) |
