STRINGSTRING
C01B4.6 C01B4.6 pdhb-1 pdhb-1 dlat-2 dlat-2 acs-19 acs-19 C50D2.7 C50D2.7 pfk-1.2 pfk-1.2 D2063.1 D2063.1 aldo-2 aldo-2 alh-9 alh-9 ldh-1 ldh-1 hxk-1 hxk-1 dlat-1 dlat-1 pyk-1 pyk-1 gpd-4 gpd-4 alh-11 alh-11 alh-1 alh-1 ipgm-1 ipgm-1 H24K24.3 H24K24.3 alh-2 alh-2 fbp-1 fbp-1 gpd-3 gpd-3 gpd-2 gpd-2 sodh-1 sodh-1 sodh-2 sodh-2 dld-1 dld-1 R05F9.6 R05F9.6 pck-2 pck-2 pgk-1 pgk-1 aldo-1 aldo-1 pdha-1 pdha-1 alh-4 alh-4 alh-5 alh-5 gpd-1 gpd-1 enol-1 enol-1 pck-1 pck-1 tpi-1 tpi-1 Y43F4B.5 Y43F4B.5 alh-12 alh-12 pfk-1.1 pfk-1.1 gpi-1 gpi-1 pyk-2 pyk-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C01B4.6Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (330 aa)
pdhb-1Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (352 aa)
dlat-22-oxoacid_dh domain-containing protein. (337 aa)
acs-19Acetyl-coenzyme A synthetase. (680 aa)
C50D2.7Probable ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. (502 aa)
pfk-1.2ATP-dependent 6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (756 aa)
D2063.1PKS_ER domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family. (350 aa)
aldo-2Fructose-bisphosphate aldolase 2. (366 aa)
alh-9Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family. (531 aa)
ldh-1L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. LDH family. (336 aa)
hxk-1Phosphotransferase; Belongs to the hexokinase family. (500 aa)
dlat-1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (507 aa)
pyk-1Pyruvate kinase; Belongs to the pyruvate kinase family. (913 aa)
gpd-4Glyceraldehyde-3-phosphate dehydrogenase 4. (341 aa)
alh-11Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (687 aa)
alh-1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
ipgm-12,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (539 aa)
H24K24.3Alcohol dehydrogenase class-3; Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (By similarity). Plays a role in the calcium flux to the cytoplasm in the ASJ sensory neurons upon removal of a nitric oxide stimulus. (386 aa)
alh-2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (514 aa)
fbp-1FBPase domain-containing protein; Belongs to the FBPase class 1 family. (341 aa)
gpd-3Glyceraldehyde-3-phosphate dehydrogenase 3. (341 aa)
gpd-2Glyceraldehyde-3-phosphate dehydrogenase 2. (341 aa)
sodh-1Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. (349 aa)
sodh-2Alcohol dehydrogenase 2; Belongs to the zinc-containing alcohol dehydrogenase family. (351 aa)
dld-1Dihydrolipoyl dehydrogenase, mitochondrial. (495 aa)
R05F9.6Uncharacterized protein; Belongs to the phosphohexose mutase family. (568 aa)
pck-2Phosphoenolypyruvate CarboxyKinase. (654 aa)
pgk-1Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
aldo-1Fructose-bisphosphate aldolase 1. (365 aa)
pdha-1Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (414 aa)
alh-4Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
alh-5Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (437 aa)
gpd-1Glyceraldehyde-3-phosphate dehydrogenase 1. (341 aa)
enol-1Enolase; Belongs to the enolase family. (465 aa)
pck-1PEPCK_GTP domain-containing protein. (651 aa)
tpi-1Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (247 aa)
Y43F4B.5Uncharacterized protein; Belongs to the phosphohexose mutase family. (595 aa)
alh-12Aldedh domain-containing protein. (499 aa)
pfk-1.1ATP-dependent 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (814 aa)
gpi-1Glucose-6-phosphate isomerase; Belongs to the GPI family. (586 aa)
pyk-2Pyruvate kinase; Belongs to the pyruvate kinase family. (515 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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