node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C05C10.3 | T02G5.7 | C05C10.3.1 | T02G5.7.1 | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.985 |
C05C10.3 | Y71G12B.10 | C05C10.3.1 | Y71G12B.10.1 | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Pyruvate carboxyltransferase domain-containing protein. | 0.981 |
C05C10.3 | hmgs-1 | C05C10.3.1 | F25B4.6.1 | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.956 |
C05C10.3 | kat-1 | C05C10.3.1 | T02G5.8.2 | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.988 |
T02G5.7 | C05C10.3 | T02G5.7.1 | C05C10.3.1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.985 |
T02G5.7 | Y71G12B.10 | T02G5.7.1 | Y71G12B.10.1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate carboxyltransferase domain-containing protein. | 0.968 |
T02G5.7 | hmgs-1 | T02G5.7.1 | F25B4.6.1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |
T02G5.7 | kat-1 | T02G5.7.1 | T02G5.8.2 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.912 |
Y71G12B.10 | C05C10.3 | Y71G12B.10.1 | C05C10.3.1 | Pyruvate carboxyltransferase domain-containing protein. | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.981 |
Y71G12B.10 | T02G5.7 | Y71G12B.10.1 | T02G5.7.1 | Pyruvate carboxyltransferase domain-containing protein. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.968 |
Y71G12B.10 | hmgs-1 | Y71G12B.10.1 | F25B4.6.1 | Pyruvate carboxyltransferase domain-containing protein. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.993 |
Y71G12B.10 | kat-1 | Y71G12B.10.1 | T02G5.8.2 | Pyruvate carboxyltransferase domain-containing protein. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.961 |
hmgs-1 | C05C10.3 | F25B4.6.1 | C05C10.3.1 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.956 |
hmgs-1 | T02G5.7 | F25B4.6.1 | T02G5.7.1 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
hmgs-1 | Y71G12B.10 | F25B4.6.1 | Y71G12B.10.1 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Pyruvate carboxyltransferase domain-containing protein. | 0.993 |
hmgs-1 | kat-1 | F25B4.6.1 | T02G5.8.2 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
kat-1 | C05C10.3 | T02G5.8.2 | C05C10.3.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.988 |
kat-1 | T02G5.7 | T02G5.8.2 | T02G5.7.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.912 |
kat-1 | Y71G12B.10 | T02G5.8.2 | Y71G12B.10.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate carboxyltransferase domain-containing protein. | 0.961 |
kat-1 | hmgs-1 | T02G5.8.2 | F25B4.6.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |