STRINGSTRING
ckb-3 ckb-3 ckb-1 ckb-1 ckb-2 ckb-2 psd-1 psd-1 C03H5.4 C03H5.4 pld-1 pld-1 C07E3.9 C07E3.9 mboa-4 mboa-4 cdgs-1 cdgs-1 pcyt-2.2 pcyt-2.2 cka-2 cka-2 mboa-3 mboa-3 pcyt-1 pcyt-1 acl-6 acl-6 F09G2.8 F09G2.8 plpp-1.3 plpp-1.3 mboa-7 mboa-7 crls-1 crls-1 acl-11 acl-11 dgk-4 dgk-4 dgk-2 dgk-2 ipla-2 ipla-2 gpdh-1 gpdh-1 acl-4 acl-4 plpp-1.1 plpp-1.1 pmt-2 pmt-2 F54D7.2 F54D7.2 dgk-3 dgk-3 bus-18 bus-18 acl-1 acl-1 lpin-1 lpin-1 ath-1 ath-1 dgk-5 dgk-5 acl-14 acl-14 gpcp-1 gpcp-1 gpdh-2 gpdh-2 M05B5.4 M05B5.4 acl-5 acl-5 mboa-6 mboa-6 eppl-1 eppl-1 T05C3.6 T05C3.6 gpcp-2 gpcp-2 acl-8 acl-8 acl-2 acl-2 T25G3.4 T25G3.4 ckc-1 ckc-1 pssy-2 pssy-2 plpp-1.2 plpp-1.2 ipla-3 ipla-3 ace-1 ace-1 pcyt-2.1 pcyt-2.1 ace-2 ace-2 acl-7 acl-7 pisy-1 pisy-1 ace-4 ace-4 pgs-1 pgs-1 cha-1 cha-1 pssy-1 pssy-1 ZK370.4 ZK370.4 acl-9 acl-9 acl-3 acl-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ckb-3Putative choline kinase B3; Belongs to the choline/ethanolamine kinase family. (368 aa)
ckb-1Choline kinase B1; Belongs to the choline/ethanolamine kinase family. (371 aa)
ckb-2Choline kinase B2; Catalyzes the first step in phosphatidylcholine biosynthesis. Phosphorylates choline. (369 aa)
psd-1Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (377 aa)
C03H5.4Phospholipase A(2). (160 aa)
pld-1Phospholipase. (1427 aa)
C07E3.9Phospholipase A(2). (153 aa)
mboa-4Membrane Bound O-Acyl transferase, MBOAT; Belongs to the membrane-bound acyltransferase family. (511 aa)
cdgs-1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns); Belongs to the CDS family. (465 aa)
pcyt-2.2CTP_transf_like domain-containing protein. (361 aa)
cka-2Choline kinase A2; Catalyzes the first step in phosphatidylcholine biosynthesis. May contribute to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine but the activity is much higher with choline. Belongs to the choline/ethanolamine kinase family. (429 aa)
mboa-3Membrane Bound O-Acyl transferase, MBOAT; Belongs to the membrane-bound acyltransferase family. (480 aa)
pcyt-1Putative choline-phosphate cytidylyltransferase; Belongs to the cytidylyltransferase family. (362 aa)
acl-6Probable glycerol-3-phosphate acyltransferase, mitochondrial; Belongs to the GPAT/DAPAT family. (718 aa)
F09G2.8Probable phospholipase D F09G2.8. (554 aa)
plpp-1.3AcidPPc domain-containing protein. (304 aa)
mboa-7Lysophospholipid acyltransferase 7; Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acyl-sn-glycero-3-phosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA or eicosapentaenoic acid (EPA) as the acyl donor. Prefers sn-2-LPI rather than sn-1-LPI as the acyl acceptor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. (453 aa)
crls-1Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (246 aa)
acl-11PlsC domain-containing protein. (368 aa)
dgk-4Diacylglycerol kinase. (1339 aa)
dgk-2Diacylglycerol kinase. (536 aa)
ipla-2Intracelllar PhosphoLipase A family. (1071 aa)
gpdh-1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (374 aa)
acl-4PlsC domain-containing protein. (617 aa)
plpp-1.1AcidPPc domain-containing protein. (385 aa)
pmt-2Phosphoethanolamine MethylTransferase. (437 aa)
F54D7.2EthanolaminePhosphoTransferase 1 homolog. (393 aa)
dgk-3Probable diacylglycerol kinase 3; Involved in AFD-neuron mediated thermotaxis. Regulates behavior to environmental temperature. Thought to have a role in olfactory adaptation by affecting diacylglycerol levels. Belongs to the eukaryotic diacylglycerol kinase family. (795 aa)
bus-18PlsC domain-containing protein. (391 aa)
acl-1Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. (262 aa)
lpin-1LNS2 domain-containing protein. (794 aa)
ath-1Abhydrolase_2 domain-containing protein. (304 aa)
dgk-5Putative diacylglycerol kinase K06A1.6. (1150 aa)
acl-14PlsC domain-containing protein. (415 aa)
gpcp-1Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 1. (690 aa)
gpdh-2Probable glycerol-3-phosphate dehydrogenase 2. (392 aa)
M05B5.4Uncharacterized protein. (417 aa)
acl-5PlsC domain-containing protein. (512 aa)
mboa-6Lysophospholipid acyltransferase 5; Probable acyltransferase which may mediate the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). May also catalyze the conversion of lysophosphatidylethanolamine (1-acyl-2-hydroxy-sn-glycero-3- phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl- sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity), as well as the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) in [...] (473 aa)
eppl-1Ethanolamine-phosphate phospho-lyase homolog 1. (467 aa)
T05C3.6Uncharacterized protein. (504 aa)
gpcp-2Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 2. (796 aa)
acl-8PlsC domain-containing protein. (372 aa)
acl-2Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. (282 aa)
T25G3.4Probable glycerol-3-phosphate dehydrogenase, mitochondrial. (722 aa)
ckc-1Choline Kinase C. (342 aa)
pssy-2PhosphatidylSerine SYnthase. (502 aa)
plpp-1.2Phospholipid phosphatase homolog 1.2 homolog. (358 aa)
ipla-3Intracelllar PhosphoLipase A family. (1047 aa)
ace-1Acetylcholinesterase 1; Rapidly hydrolyzes choline released into the synapse. It can hydrolyze butyrylthiocholine. (620 aa)
pcyt-2.1CTP_transf_like domain-containing protein. (391 aa)
ace-2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (629 aa)
acl-7Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. (671 aa)
pisy-1CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (220 aa)
ace-4Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (602 aa)
pgs-1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (446 aa)
cha-1Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses (By similarity). Required in SIA sublateral cholinergic motor neurons for a left-right turning behavior that occurs during the lethargus phase of the normal sleep process called 'flipping'. During 'flipping' animals rotate 180 degrees about their longitudinal axis ; Belongs to the carnitine/choline acetyltransferase family. (627 aa)
pssy-1PhosphatidylSerine SYnthase. (507 aa)
ZK370.4Uncharacterized NTE family protein ZK370.4; Belongs to the NTE family. (1353 aa)
acl-9PlsC domain-containing protein. (399 aa)
acl-3Tafazzin family protein; Belongs to the taffazin family. (284 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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