STRINGSTRING
B0272.3 B0272.3 C05C10.3 C05C10.3 ech-1.1 ech-1.1 ech-8 ech-8 ech-9 ech-9 hmgs-1 hmgs-1 alh-7 alh-7 F54C8.1 F54C8.1 sur-5 sur-5 gta-1 gta-1 hacd-1 hacd-1 T02G5.7 T02G5.7 kat-1 kat-1 ech-6 ech-6 ech-1.2 ech-1.2 ech-7 ech-7 unc-25 unc-25 Y45G12B.3 Y45G12B.3 Y71G12B.10 Y71G12B.10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B0272.3Probable 3-hydroxyacyl-CoA dehydrogenase B0272.3; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (309 aa)
C05C10.3Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (521 aa)
ech-1.1Enoyl-CoA Hydratase. (755 aa)
ech-8Enoyl-CoA Hydratase. (437 aa)
ech-9Enoyl-CoA Hydratase. (434 aa)
hmgs-1Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (462 aa)
alh-7Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
F54C8.1Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (298 aa)
sur-5Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA (By similarity). Negatively regulates let-60 Ras activity during vulval induction. Belongs to the ATP-dependent AMP-binding enzyme family. (700 aa)
gta-1Probable 4-aminobutyrate aminotransferase, mitochondrial. (483 aa)
hacd-1Hydroxy-Acyl-CoA Dehydrogenase. (299 aa)
T02G5.7Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
kat-1Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
ech-6Probable enoyl-CoA hydratase, mitochondrial. (288 aa)
ech-1.2Enoyl-CoA Hydratase. (781 aa)
ech-7Enoyl-CoA Hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
unc-25Glutamic acid decarboxylase. (508 aa)
Y45G12B.3L-2-hydroxyglutarate dehydrogenase, mitochondrial. (433 aa)
Y71G12B.10Pyruvate carboxyltransferase domain-containing protein. (318 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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