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dpyd-1 dpyd-1 pnk-4 pnk-4 dhp-2 dhp-2 upb-1 upb-1 F25H9.6 F25H9.6 alh-1 alh-1 bcat-1 bcat-1 alh-2 alh-2 dhp-1 dhp-1 T04G9.4 T04G9.4 T05G5.5 T05G5.5 alh-4 alh-4 alh-5 alh-5 T28H10.1 T28H10.1 Y44A6D.5 Y44A6D.5 Y65B4A.8 Y65B4A.8 Y71H2AM.6 Y71H2AM.6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dpyd-1Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). Involved in the degradation of the chemotherapeutic drug 5-fluorouracil. (1059 aa)
pnk-4Pantothenate kinase; Belongs to the type II pantothenate kinase family. (755 aa)
dhp-2Dihydropyrimidinase 2; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. (520 aa)
upb-1CN hydrolase domain-containing protein. (387 aa)
F25H9.6Flavoprotein domain-containing protein. (237 aa)
alh-1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
bcat-1Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (415 aa)
alh-2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (514 aa)
dhp-1Dihydropyrimidinase 1. (489 aa)
T04G9.4ACPS domain-containing protein. (297 aa)
T05G5.5Uncharacterized protein T05G5.5; Belongs to the CoaE family. (246 aa)
alh-4Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
alh-5Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (437 aa)
T28H10.1ACPS domain-containing protein. (285 aa)
Y44A6D.5Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (393 aa)
Y65B4A.8CTP_transf_like domain-containing protein. (461 aa)
Y71H2AM.6Uncharacterized protein. (277 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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