STRINGSTRING
fce-1 fce-1 coq-1 coq-1 hmgr-1 hmgr-1 icmt-1 icmt-1 fntb-1 fntb-1 hmgs-1 hmgs-1 F32D8.13 F32D8.13 fce-2 fce-2 idi-1 idi-1 M01E11.1 M01E11.1 fnta-1 fnta-1 fdps-1 fdps-1 T01G1.4 T01G1.4 T02G5.7 T02G5.7 kat-1 kat-1 mvk-1 mvk-1 Y48B6A.13 Y48B6A.13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fce-1CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (442 aa)
coq-1COenzyme Q (Ubiquinone) biosynthesis; Belongs to the FPP/GGPP synthase family. (393 aa)
hmgr-13-hydroxy-3-methylglutaryl coenzyme A reductase. (550 aa)
icmt-1Protein-S-isoprenylcysteine O-methyltransferase. (295 aa)
fntb-1Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (401 aa)
hmgs-1Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (462 aa)
F32D8.13Uncharacterized protein. (194 aa)
fce-2CAAX prenyl protease 2 homolog; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins; Belongs to the peptidase U48 family. (266 aa)
idi-1Nudix hydrolase domain-containing protein. (236 aa)
M01E11.1Protein-S-isoprenylcysteine O-methyltransferase. (293 aa)
fnta-1FarNesylTransferase, Alpha subunit. (328 aa)
fdps-1Farnesyl DiPhosphate Synthetase; Belongs to the FPP/GGPP synthase family. (352 aa)
T01G1.4Alkyl transferase; Belongs to the UPP synthase family. (299 aa)
T02G5.7Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
kat-1Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
mvk-1MeValonate Kinase. (614 aa)
Y48B6A.13Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (377 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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