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dars-1 dars-1 iars-2 iars-2 rars-2 rars-2 tars-1 tars-1 sars-1 sars-1 secs-1 secs-1 dars-2 dars-2 fars-3 fars-3 nars-1 nars-1 rars-1 rars-1 aars-2 aars-2 mars-1 mars-1 yars-2 yars-2 iars-1 iars-1 lars-1 lars-1 kars-1 kars-1 ears-2 ears-2 fars-1 fars-1 gars-1 gars-1 hars-1 hars-1 pars-1 pars-1 pars-2 pars-2 aars-1 aars-1 sars-2 sars-2 yars-1 yars-1 Y105E8A.20 Y105E8A.20 cars-1 cars-1 Y41D4A.6 Y41D4A.6 qars-1 qars-1 pstk-1 pstk-1 fars-2 fars-2 nars-2 nars-2 Y66D12A.7 Y66D12A.7 wars-1 wars-1 glp-4 glp-4 ears-1 ears-1 vars-1 vars-1 lars-2 lars-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dars-1Aspartate--tRNA ligase, cytoplasmic. (531 aa)
iars-2Isoleucyl Amino-acyl tRNA Synthetase. (970 aa)
rars-2DALR_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (512 aa)
tars-1Threonine--tRNA ligase, cytoplasmic; Belongs to the class-II aminoacyl-tRNA synthetase family. (725 aa)
sars-1Probable serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec) (By similarity). (487 aa)
secs-1O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family. (523 aa)
dars-2AA_TRNA_LIGASE_II domain-containing protein. (593 aa)
fars-3Phenylalanine--tRNA ligase beta subunit. (591 aa)
nars-1Asparagine--tRNA ligase, cytoplasmic; Involved in protein synthesis. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Belongs to the class-II aminoacyl-tRNA synthetase family. (545 aa)
rars-1Probable arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. (713 aa)
aars-2Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
mars-1Methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (917 aa)
yars-2Tyrosine--tRNA ligase. (447 aa)
iars-1Isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1141 aa)
lars-1Leucine--tRNA ligase; Involved in protein synthesis. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. (1186 aa)
kars-1Lysine--tRNA ligase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. (596 aa)
ears-2tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (481 aa)
fars-1AA_TRNA_LIGASE_II domain-containing protein. (552 aa)
gars-1Glycine--tRNA ligase; Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis. Belongs to the class-II aminoacyl-tRNA synthetase family. (742 aa)
hars-1Histidine--tRNA ligase; Involved in protein synthesis. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (Probable). Required for germ cell development. Belongs to the class-II aminoacyl-tRNA synthetase family. (524 aa)
pars-1Prolyl Amino-acyl tRNA Synthetase. (581 aa)
pars-2AA_TRNA_LIGASE_II domain-containing protein. (454 aa)
aars-1Alanine--tRNA ligase, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (793 aa)
sars-2AA_TRNA_LIGASE_II domain-containing protein. (441 aa)
yars-1Tyrosine--tRNA ligase. (722 aa)
Y105E8A.20tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (524 aa)
cars-1tRNA-synt_1e domain-containing protein. (909 aa)
Y41D4A.6Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (454 aa)
qars-1Probable glutamine--tRNA ligase. (786 aa)
pstk-1Phosphoryl Seryl-TRNA (Ser/Sec) Kinase. (259 aa)
fars-2Mitochondrial phenylalanyl-tRNA synthetase. (458 aa)
nars-2AA_TRNA_LIGASE_II domain-containing protein. (418 aa)
Y66D12A.7Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). (175 aa)
wars-1Tryptophanyl(W) Amino-acyl tRNA Synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (417 aa)
glp-4Valine--tRNA ligase. (1050 aa)
ears-1Glutamyl(E) Amino-acyl tRNA Synthetase. (1149 aa)
vars-1Valyl Amino-acyl tRNA Synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (978 aa)
lars-2Anticodon_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (859 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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