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| | aly-1 | FoP_duplication domain-containing protein. (223 aa) |
| | C02B10.4 | RRM domain-containing protein. (211 aa) |
| | mog-4 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4; ATP-binding RNA helicase involved in pre-mRNA splicing (Probable). Operates during embryogenesis. (1008 aa) |
| | bud-31 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. (147 aa) |
| | C07H6.4 | Uncharacterized protein. (933 aa) |
| | sap-49 | Splicing factor 3B subunit 4; Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (By similarity). (388 aa) |
| | hsp-70 | Heat Shock Protein; Belongs to the heat shock protein 70 family. (643 aa) |
| | thoc-2 | THO Complex (Transcription factor/nuclear export) subunit. (1437 aa) |
| | rsp-8 | RRM domain-containing protein. (309 aa) |
| | snrp-40.2 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | hel-1 | Spliceosome RNA helicase DDX39B homolog; Required for mRNA export out of the nucleus. May play a role in spliceosome assembly. (425 aa) |
| | rsp-6 | Probable splicing factor, arginine/serine-rich 6; Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaprodites. Required for the development of somatic gonad structures and for progression from larval stage to adulthood; Belongs to the splicing factor SR family. (179 aa) |
| | cyn-12 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (169 aa) |
| | prp-4 | WD_REPEATS_REGION domain-containing protein. (496 aa) |
| | acin-1 | ACINus (Mammalian Apoptotic Chromatin condensation Inducer in the Nucleus) homolog. (580 aa) |
| | C46F11.4 | Uncharacterized protein. (811 aa) |
| | prp-8 | Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. (2329 aa) |
| | C50D2.5 | Splicing factor 3B subunit 6-like protein; Necessary for the splicing of pre-mRNA. (138 aa) |
| | syf-1 | SYF pre-mRNA splicing factor homolog. (855 aa) |
| | snr-4 | Probable small nuclear ribonucleoprotein Sm D2; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity). (118 aa) |
| | prp-38 | Yeast PRP (Splicing factor) related. (320 aa) |
| | plrg-1 | WD_REPEATS_REGION domain-containing protein. (494 aa) |
| | cdc-5L | Cell Division Cycle related. (755 aa) |
| | mog-5 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5; Could act late in the splicing of pre-mRNA and mediate the release of the spliced mRNA from spliceosomes; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily. (1200 aa) |
| | rsp-4 | Probable splicing factor, arginine/serine-rich 4; May play a functionally redundant role in embryogenesis. Belongs to the splicing factor SR family. (196 aa) |
| | ddx-23 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (730 aa) |
| | F08B4.7 | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (142 aa) |
| | snrp-40.1 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | usp-39 | Ubiquitin Specific Protease. (602 aa) |
| | repo-1 | Matrin-type domain-containing protein. (222 aa) |
| | F11F1.1 | DUF148 domain-containing protein; Belongs to the heat shock protein 70 family. (607 aa) |
| | F19F10.9 | Uncharacterized protein. (829 aa) |
| | aly-2 | FoP_duplication domain-containing protein. (227 aa) |
| | ncbp-2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap stru [...] (158 aa) |
| | hrpk-1 | Heterogeneous nuclear ribonucleoprotein K homolog; RNA-binding protein which functions together with alg-1, a component of the miRNA loading complex, to modulate the processing and activity of specific miRNAs such as miR-58 and let-7 to regulate gene expression at the post-transcriptional level during embryonic, hypodermal and neuronal development. Promotes the lsy-6-mediated repression of cog-1 in uterine cells. In embryos, may play a role in the DNA damage response. (397 aa) |
| | hsp-1 | Heat shock 70 kDa protein A. (640 aa) |
| | lsm-5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA; Belongs to the snRNP Sm proteins family. (91 aa) |
| | lsm-4 | Probable U6 snRNA-associated Sm-like protein LSm4; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (123 aa) |
| | F32B6.3 | SFM domain-containing protein. (352 aa) |
| | thoc-3 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | F33D11.10 | Uncharacterized protein; Belongs to the DEAD box helicase family. (399 aa) |
| | F33H1.3 | Uncharacterized protein F33H1.3. (359 aa) |
| | ncbp-1 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-1 does not bind directly capped RNAs (m7GpppG- capped RNA) but is required to stabilize the movement of the N-terminal loop of ncbp-2 and lock the CBC into a high affinity cap-binding state with the c [...] (798 aa) |
| | F44E5.4 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (645 aa) |
| | prp-17 | WD_REPEATS_REGION domain-containing protein. (567 aa) |
| | isy-1 | Protein isy-1; Regulates the processing of the mir-60 microRNA (miRNA), which in turn negatively regulates the expression of the transcription factor zip-10. Does not affect the splicing of zip-10 ; Belongs to the ISY1 family. (267 aa) |
| | ddx-15 | Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. (739 aa) |
| | rbm-17 | RNA Binding Motif protein homolog. (371 aa) |
| | ddx-17 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (561 aa) |
| | tag-65 | SR-related CTD associated factor 6. (675 aa) |
| | mog-2 | Probable U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Required maternally for early embryonic development and zygotically for germline and somatic development. Has a role in the switch from mitosis to meiosis. Might function in alternative splicing. (253 aa) |
| | teg-4 | CPSF_A domain-containing protein. (1220 aa) |
| | mog-1 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. (1131 aa) |
| | rnp-7 | RRM domain-containing protein. (332 aa) |
| | syf-2 | Pre-mRNA-splicing factor syf-2; May be involved in pre-mRNA splicing. (234 aa) |
| | K07C5.6 | Pre-mRNA-splicing factor SLU7; Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Belongs to the SLU7 family. (647 aa) |
| | rnp-3 | RNP (RRM RNA binding domain) containing. (217 aa) |
| | rnp-2 | RNP (RRM RNA binding domain) containing. (206 aa) |
| | M01E11.2 | DUF1716 domain-containing protein. (544 aa) |
| | prp-3 | Yeast PRP (Splicing factor) related. (621 aa) |
| | M03F8.3 | Uncharacterized protein. (747 aa) |
| | aly-3 | FoP_duplication domain-containing protein. (240 aa) |
| | M28.5 | NHP2-like protein 1 homolog; Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding (By similarity); Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | snrp-27 | SNRNP27 domain-containing protein. (155 aa) |
| | rnp-4 | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (142 aa) |
| | mag-1 | Protein mago nashi homolog; Involved in hermaphrodite germline sex determination. May allow oogenesis by inhibiting the function of one or more of the masculinizing genes (fog, fem, and gld) which act during the fourth larval stage to promote transient sperm production in the hermaphrodite germline; Belongs to the mago nashi family. (152 aa) |
| | cyn-11 | Peptidyl-prolyl cis-trans isomerase 11; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. PPIase H subfamily. (183 aa) |
| | thoc-1 | THO Complex (Transcription factor/nuclear export) subunit. (665 aa) |
| | sftb-1 | SF3b1 domain-containing protein. (1322 aa) |
| | cwc-15 | Spliceosome-associated protein CWC15 homolog; Component of a spliceosomal complex that is required for activating pre-mRNA splicing. (230 aa) |
| | prp-19 | Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs. Belongs to the WD repeat PRP19 family. (492 aa) |
| | gut-2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (97 aa) |
| | rbm-22 | RNA Binding Motif protein homolog. (408 aa) |
| | bcas-2 | BCAS splicing factor homolog. (238 aa) |
| | T13H5.4 | Matrin-type domain-containing protein. (500 aa) |
| | pqbp-1.1 | WW domain-containing protein. (280 aa) |
| | skp-1 | Uncharacterized protein T27F2.1. (535 aa) |
| | snr-3 | Probable small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures (By similarity). Belongs to the snRNP core protein family. (126 aa) |
| | rsp-2 | Probable splicing factor, arginine/serine-rich 2; Plays a functionally redundant role in spermatogenesis and growth rate control. Required for the development of somatic gonad structures and for progression from larval stage to adulthood. Belongs to the splicing factor SR family. (281 aa) |
| | rsp-1 | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. (312 aa) |
| | sftb-2 | PSP domain-containing protein. (602 aa) |
| | rbm-25 | PWI domain-containing protein. (707 aa) |
| | prp-21 | Yeast PRP (Splicing factor) related. (655 aa) |
| | snr-2 | Probable small nuclear ribonucleoprotein-associated protein B; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure (By similarity); Belongs to the snRNP SmB/SmN family. (160 aa) |
| | Y108G3AL.2 | Uncharacterized protein. (327 aa) |
| | prp-31 | Nop domain-containing protein. (504 aa) |
| | rsp-3 | Probable splicing factor, arginine/serine-rich 3; Plays an essential role in embryogenesis. (258 aa) |
| | cyn-13 | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. (331 aa) |
| | uaf-2 | U2AF splicing factor. (285 aa) |
| | snr-1 | Small nuclear ribonucleoprotein Sm D3; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity); Belongs to the snRNP core protein family. (136 aa) |
| | snrp-200 | Putative U5 small nuclear ribonucleoprotein 200 kDa helicase; Putative RNA helicase involved in the second step of RNA splicing; Belongs to the helicase family. SKI2 subfamily. (2145 aa) |
| | rnp-6 | RNP (RRM RNA binding domain) containing. (749 aa) |
| | snr-6 | Probable small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (90 aa) |
| | phf-5 | PHd Finger family. (110 aa) |
| | Y54G2A.75 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | prp-6 | Yeast PRP (Splicing factor) related. (968 aa) |
| | lsm-3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | Y65B4A.6 | Uncharacterized protein; Belongs to the DEAD box helicase family. (399 aa) |
| | Y69A2AR.21 | Uncharacterized protein. (169 aa) |
| | smr-1 | SMN (Survival of Motor Neuron protein) Related. (239 aa) |
| | snr-7 | Probable small nuclear ribonucleoprotein G; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (77 aa) |
| | lsm-6 | Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (77 aa) |
| | lsm-8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa) |
| | emb-4 | Uncharacterized protein. (1467 aa) |
| | uaf-1 | Splicing factor U2AF 65 kDa subunit; Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity). (496 aa) |
| | ZK1098.1 | WW domain-containing protein ZK1098.1. (724 aa) |
| | tcer-1 | WW domain-containing protein. (914 aa) |
| | eftu-2 | Tr-type G domain-containing protein. (974 aa) |
| | lsm-7 | Sm domain-containing protein. (104 aa) |
| | snr-5 | Probable small nuclear ribonucleoprotein F; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. (85 aa) |
| | snu-23 | Putative zinc finger matrin-type protein snu-23. (217 aa) |
