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| | asm-1 | Sphingomyelin phosphodiesterase 1; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (564 aa) |
| | cln-3.2 | Battenin. (435 aa) |
| | lmp-1 | LAMP family protein lmp-1; Belongs to the LAMP family. (237 aa) |
| | pho-10 | Putative acid phosphatase 10. (411 aa) |
| | pho-11 | Putative acid phosphatase 11. (413 aa) |
| | nuc-1 | Deoxyribonuclease-2; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Implicated in apoptosis. Belongs to the DNase II family. (375 aa) |
| | cpr-6 | Cathepsin B-like cysteine proteinase 6; Belongs to the peptidase C1 family. (379 aa) |
| | vha-7 | V-type proton ATPase subunit a. (1210 aa) |
| | C27A2.12 | Uncharacterized protein; Belongs to the histidine acid phosphatase family. (460 aa) |
| | pho-12 | Intestinal acid PHOsphatase; Belongs to the histidine acid phosphatase family. (407 aa) |
| | spp-10 | SaPosin-like Protein family. (429 aa) |
| | C29E4.10 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. (645 aa) |
| | vha-16 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (348 aa) |
| | gba-1 | Putative glucosylceramidase 1. (523 aa) |
| | gba-2 | Putative glucosylceramidase 2; Belongs to the glycosyl hydrolase 30 family. (516 aa) |
| | C33G3.4 | Probable beta-mannosidase; Belongs to the glycosyl hydrolase 2 family. (900 aa) |
| | ctns-1 | Cystinosin homolog; Thought to transport cystine out of lysosomes (By similarity). May play a role in the degradation of engulfed apoptotic cells. (404 aa) |
| | cpr-1 | Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family. (329 aa) |
| | pho-1 | Intestinal acid phosphatase; Acid phosphatase required for normal growth and development. Specifically required for normal gut differentiation. (449 aa) |
| | ncr-1 | NPC intracellular cholesterol transporter 1 homolog 1; Involved in the uptake or utilization of cholesterol (By similarity). Ncr-1 and ncr-2 act redundantly to prevent dauer larva formation under favorable growth conditions, and are required for the normal functioning of ADF, ASI and ASG neurons. Belongs to the patched family. (1383 aa) |
| | F02E9.7 | Metallophos domain-containing protein. (419 aa) |
| | cln-3.1 | Battenin. (424 aa) |
| | pho-13 | Intestinal acid PHOsphatase; Belongs to the histidine acid phosphatase family. (446 aa) |
| | crn-7 | Cell-death-related nuclease 7; Belongs to the DNase II family. (367 aa) |
| | gba-3 | Putative glucosylceramidase 3. (525 aa) |
| | F13D12.6 | Serine carboxypeptidase ctsa-1.2; Belongs to the peptidase S10 family. (454 aa) |
| | F14D7.6 | MFS domain-containing protein. (487 aa) |
| | F26C11.1 | Putative acid phosphatase F26C11.1. (435 aa) |
| | asah-2 | Probable acid ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (401 aa) |
| | aps-1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa) |
| | cpz-1 | Cathepsin Z-1; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. Probably, required for the degradation of the old cuticle. Belongs to the peptidase C1 family. (306 aa) |
| | F32H5.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (356 aa) |
| | vha-5 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa) |
| | cpr-2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (326 aa) |
| | F36G3.3 | LITAF domain-containing protein. (148 aa) |
| | F41C3.5 | Serine carboxypeptidase ctsa-1.1; Belongs to the peptidase S10 family. (469 aa) |
| | tag-196 | Uncharacterized protein; Belongs to the peptidase C1 family. (477 aa) |
| | cpr-4 | Cathepsin B-like cysteine proteinase 4; Thiol protease which shows activity against the fluorogenic substrate z-Arg-Arg-AMC; Belongs to the peptidase C1 family. (335 aa) |
| | ppt-1 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides. (298 aa) |
| | vha-18 | Probable V-type proton ATPase subunit H 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). (451 aa) |
| | apm-3 | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (414 aa) |
| | lipl-1 | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (405 aa) |
| | apm-1 | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (426 aa) |
| | aman-1 | Alpha-mannosidase. (955 aa) |
| | F57F5.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (351 aa) |
| | asp-3 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. (398 aa) |
| | crn-6 | Cell death-related nuclease 6; Involved in the degradation of chromosomal DNA. Contributes to cell killing; Belongs to the DNase II family. (378 aa) |
| | K09E4.4 | Uncharacterized protein. (715 aa) |
| | asah-1 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH. (393 aa) |
| | unc-101 | AP-1 complex subunit mu-1-I; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development and behavior, including negative regulation of vulval differentiation. Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9. (422 aa) |
| | smf-2 | NRAMP-like transporter smf-2; Probable divalent metal ion transporter which regulates Mn(2+) uptake. (546 aa) |
| | smf-1 | NRAMP-like transporter smf-1; Probable divalent metal ion transporter which regulates Mn(2+) uptake; Belongs to the NRAMP family. (562 aa) |
| | cpz-2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (467 aa) |
| | M05B5.4 | Uncharacterized protein. (417 aa) |
| | R04B3.2 | Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. (363 aa) |
| | gana-1 | Alpha-galactosidase. (451 aa) |
| | mig-23 | Nucleoside-diphosphatase mig-23; Seems to be able to hydrolyze ADP, UDP and GDP. Supports mig- 17 glycosylation and surface expression, which is required for proper migration of distal tip cells during gonad morphogenesis. (552 aa) |
| | vha-2 | V-type proton ATPase 16 kDa proteolipid subunit 2; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase (By similarity). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occ [...] (161 aa) |
| | vha-1 | V-type proton ATPase 16 kDa proteolipid subunit 1; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The introduction of sperm triggers V-AT [...] (169 aa) |
| | apb-3 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (945 aa) |
| | asp-4 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. (444 aa) |
| | heh-1 | Putative protein heh-1. (154 aa) |
| | vha-4 | Vacuolar H ATPase. (214 aa) |
| | cpl-1 | Cathepsin L-like; Cysteine protease which plays an essential role in the degradation of proteins in lysosomes. During early embryogenesis, maternally required for the proteolytic processing of yolk proteins in platelets, a lysosome- like structure where a slow and controlled degradation of yolk proteins occurs. In the gonad, required for the clearance of apoptotic germ cells in the engulfing cell phagolysosomes. In embryos, required for the degradation of endocytic and autophagic cargos. In embryos, may play a role in the degradation of lipid-containing droplets. Required for larval de [...] (337 aa) |
| | slc-17.9 | MFS domain-containing protein. (516 aa) |
| | cpr-3 | Cathepsin B-like cysteine proteinase 3; Belongs to the peptidase C1 family. (370 aa) |
| | pho-14 | Intestinal acid PHOsphatase; Belongs to the histidine acid phosphatase family. (440 aa) |
| | vha-15 | Probable V-type proton ATPase subunit H 2; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). (470 aa) |
| | hex-1 | Beta-hexosaminidase A; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines. Degrades chitotriose. (555 aa) |
| | pho-4 | Intestinal acid PHOsphatase; Belongs to the histidine acid phosphatase family. (452 aa) |
| | bgal-1 | Beta-galactosidase. (653 aa) |
| | chc-1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. (1681 aa) |
| | chhy-1 | Hyaluronidase. (458 aa) |
| | tsp-7 | Tetraspanin. (232 aa) |
| | T28H10.3 | Uncharacterized protein. (462 aa) |
| | vha-6 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (865 aa) |
| | asm-3 | Putative sphingomyelin phosphodiesterase asm-3; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (589 aa) |
| | W03G11.3 | Putative alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. (482 aa) |
| | haf-4 | HAlF transporter (PGP related). (787 aa) |
| | apt-9 | AdaPTin or adaptin-related protein. (588 aa) |
| | cpr-8 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (335 aa) |
| | W07B8.4 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (335 aa) |
| | cpr-5 | Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family. (344 aa) |
| | apd-3 | AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1251 aa) |
| | apg-1 | AP-1 complex subunit gamma. (829 aa) |
| | Y105E8B.9 | Uncharacterized protein. (628 aa) |
| | Y16B4A.2 | Carboxypeptidase; Belongs to the peptidase S10 family. (2161 aa) |
| | ctsa-2 | Carboxypeptidase; Belongs to the peptidase S10 family. (512 aa) |
| | aps-3 | Clat_adaptor_s domain-containing protein. (192 aa) |
| | scav-3 | SCAVenger receptor (CD36 family) related; Belongs to the CD36 family. (534 aa) |
| | gba-4 | Putative glucosylceramidase 4; Belongs to the glycosyl hydrolase 30 family. (519 aa) |
| | haf-7 | HAlF transporter (PGP related). (807 aa) |
| | Y53G8AR.7 | MFS domain-containing protein. (519 aa) |
| | vha-19 | Vacuolar H ATPase. (451 aa) |
| | smf-3 | NRAMP-like transporter smf-3; Probable divalent metal ion transporter which regulates the uptake of several heavy metals such as Mn(2+), Al(3+) and iron. Plays a role in modulating Al(3+)-induced dopamine (DA) neuron degeneration through the intracellular sequestration of Al(3+). (560 aa) |
| | scav-2 | SCAVenger receptor (CD36 family) related; Belongs to the CD36 family. (558 aa) |
| | Y87G2A.19 | LITAF domain-containing protein. (110 aa) |
| | cln-3.3 | Battenin. (417 aa) |
| | asm-2 | Sphingomyelin phosphodiesterase 2; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (618 aa) |
| | haf-9 | ABC transmembrane type-1 domain-containing protein. (815 aa) |
| | lipl-5 | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (403 aa) |
| | unc-32 | Probable V-type proton ATPase 116 kDa subunit a; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (Probable). Regulates the size of gut granules during embryonic development. (905 aa) |
