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SLG_01790 | Protocatechuate 4,5-dioxygenase alpha chain. (133 aa) | ||||
SLG_01800 | Protocatechuate 4,5-dioxygenase beta chain. (289 aa) | ||||
desB | Gallate dioxygenase. (418 aa) | ||||
ligC | 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; Involved in the degradation of protocatechuate (PCA) via the PCA 4,5-cleavage pathway. Catalyzes the oxidation of the hemiacetal form of 4-carboxy-2-hydroxymuconate-6-semialdehyde (CHMS) to produce 2- pyrone-4,6-dicarboxylate (PDC). LigC has 10-times-higher affinity to NADP than to NAD. (315 aa) | ||||
ligB | Protocatechuate 4,5-dioxygenase beta chain; Responsible for the aromatic ring fission of protocatechuate. (302 aa) | ||||
ligA-2 | Protocatechuate 4,5-dioxygenase alpha chain; Responsible for the aromatic ring fission of protocatechuate. (139 aa) | ||||
ligJ | 4-oxalomesaconate hydratase; Contributes to the degradation of lignin at the level of the protocatechuate 4,5-cleavage pathway. Catalyzes the hydration of the double bond of (3Z)-2-keto-4-carboxy-3-hexenedioate (KCH) to (4S)-4- carboxy-4-hydroxy-2-oxoadipate (CHA, also named (2S)-2-hydroxy-4- oxobutane-1,2,4-tricarboxylate). Is involved in the catabolism of both vanillate and syringate. (341 aa) | ||||
SLG_12530 | Putative phosphogluconate dehydrogenase. (297 aa) | ||||
ligR | LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (393 aa) | ||||
ligK | 4-hydroxy-4-methyl-2-oxoadipate aldolase; Contributes to the degradation of lignin, being involved in the final step of the protocatechuate 4,5-cleavage pathway. Catalyzes the conversion of 4-carboxy-4-hydroxy-2-oxoadipate (CHA, also named 2- hydroxy-4-oxobutane-1,2,4-tricarboxylate) to pyruvate and oxaloacetate but also the decarboxylation of oxaloacetate to pyruvate and CO2. Is essential for catabolism and utilization of vanillate and syringate. Is also able to catalyze the formation of 4-hydroxy- 4-methyl-2-oxoglutarate (HMG) from two molecules of pyruvate ; Belongs to the LigK/PcmE [...] (228 aa) | ||||
SLG_12560 | Hypothetical protein. (351 aa) | ||||
ligI | 2-pyrone-4,6-dicarboxylic acid hydrolase; Contributes to the degradation of lignin at the level of the protocatechuate 4,5-cleavage pathway. Catalyzes the hydrolysis of 2-pyrone-4,6-dicarboxylate (PDC) to (4E)-oxalomesaconate (OMA). The keto form of OMA can tautomerize into the enol form, 4-carboxy-2-hydroxymuconate (CHM), under certain pH conditions. Also catalyzes the reverse reaction. Is essential for the growth of Sphingobium sp. SYK-6 on vanillate but is not responsible for the growth of this strain on syringate. Belongs to the metallo-dependent hydrolases superfamily. PDC hydrola [...] (293 aa) | ||||
ligM | vanillate/3-O-methylgallate O-demethylase; Involved in the catabolism of vanillate and syringate. Catalyzes the transfer of a methyl moiety from vanillate or 3-O- methylgallate (3MGA) to tetrahydrofolate, forming protocatechuate (PCA) or gallate, respectively, and methyl-tetrahydrofolate. Has similar activities with both substrates. Cannot use syringate. Uses an ordered, sequential kinetic mechanism. (471 aa) | ||||
desZ | 3-O-methylgallate 3,4-dioxygenase. (330 aa) | ||||
SLG_31300 | Putative hydrolase. (283 aa) | ||||
SLG_37520 | Protocatechuate 4,5-dioxygenase beta chain. (286 aa) | ||||
SLG_37530 | Protocatechuate 4,5-dioxygenase alpha chain. (124 aa) |